Evidence map›Paper›PMID 33800721›Full record

ArticleInternational journal of environmental research and public health2021

COVID-19 Seroprevalence among Healthcare Workers of a Large COVID-19 Hospital in Rome Reveals Strengths and Limits of Two Different Serological Tests.

Giuseppe Vetrugno, Daniele Ignazio La Milia, Floriana D'Ambrosio, Marcello Di Pumpo, Roberta Pastorino, Stefania Boccia, Rosalba Ricci, Fabio De-Giorgio, Michela Cicconi, Federica Foti and 17 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 2 institutions in 1 country.

Giuseppe VetrugnoRisk Management Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Daniele Ignazio La MiliaHospital Health Management, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Floriana D'AmbrosioSection of Hygiene, University Department of Health Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-0347-088X
Marcello Di PumpoSection of Hygiene, University Department of Health Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Roberta PastorinoDepartment of Woman and Child Health and Public Health-Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Stefania BocciaSection of Hygiene, University Department of Health Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Rosalba RicciDepartment of Laboratory and Infectivological Sciences, Fondazione Policlinico A. Gemelli IRCCS, 00168 Rome, Italy.
Fabio De-GiorgioSection of Legal Medicine, Department of Health Care Surveillance and Bioethics, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Michela CicconiRisk Management Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Federica FotiRisk Management Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Domenico PascucciSection of Hygiene, University Department of Health Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-5804-2284
Francesco CastriniSection of Hygiene, University Department of Health Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Elettra CariniSection of Hygiene, University Department of Health Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-9422-3285
Andrea CambieriHospital Health Management, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Maria Elena D'AlfonsoHospital Health Management, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Gennaro CapalboHospital Health Management, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Massimo FantoniDepartment of Laboratory and Infectivological Sciences, Fondazione Policlinico A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-6913-8460
Umberto MoscatoSection of Hygiene, University Department of Health Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Domenico StaitiDepartment of Woman and Child Health and Public Health-Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Francesco Maria De SimoneDepartment of Woman and Child Health and Public Health-Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Filippo BerlocoHospital Health Management, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-5752-0064
Gianfranco DamianiSection of Hygiene, University Department of Health Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0003-3028-6188
Maurizio ZegaDirector of Nursing Service Technician and Rehabilitation Administration (S.I.T.R.A.), Fondazione Policlinico Universitario Agostino Gemelli, 00168 Rome, Italy.
Paola CattaniDepartment of Laboratory and Infectivological Sciences, Fondazione Policlinico A. Gemelli IRCCS, 00168 Rome, Italy.
Brunella PosteraroDepartment of Basic Biotechnological Sciences, Intensive and Perioperative Clinics, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Maurizio SanguinettiDepartment of Laboratory and Infectivological Sciences, Fondazione Policlinico A. Gemelli IRCCS, 00168 Rome, Italy.
Patrizia LaurentiSection of Hygiene, University Department of Health Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Università Cattolica del Sacro Cuore · ITAgostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthcare workers are at the forefront against COVID-19, worldwide. Since Fondazione Policlinico Universitario A. Gemelli (FPG) IRCCS was enlisted as a COVID-19 hospital, the healthcare workers deployed to COVID-19 wards were separated from those with limited/no exposure, whereas the administrative staff were designated to work from home. Between 4 June and 3 July 2020, an investigation was conducted to evaluate the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin (IgG) antibodies among the employees of the FPG using point-of-care (POC) and venous blood tests. Sensitivity, specificity, and predictive values were determined with reverse-transcription polymerase chain reaction on nasal/oropharyngeal swabs as the diagnostic gold standard. The participants enrolled amounted to 4777. Seroprevalence was 3.66% using the POC test and 1.19% using the venous blood test, with a significant difference (

Indexed as

COVID-19Antibodies, ViralHealth PersonnelHospitalsHumansRomeSARS-CoV-2Seroepidemiologic StudiesSerologic TestsAntibodies, ViralCOVID-19healthcare workerspoint-of-careSARS-CoV-2serological testsseroprevalence

Identifiers

PMID33800721
PMCPMC7967358
OpenAlexW3134409935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.