Evidence map›Paper›PMID 33800649›Full record

ArticleInternational journal of molecular sciences2021

ceRNA Network Regulation of TGF-β, WNT, FOXO, Hedgehog Pathways in the Pharynx of

Aiti Vizzini, Angela Bonura, Laura La Paglia, Antonino Fiannaca, Massimo La Rosa, Alfonso Urso, Vincenzo Arizza

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Many Faces of Next-Generation Sequencing in Gene Expression Studies.International journal of molecular sciences · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Aiti VizziniDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche-Università di Palermo, via Archirafi 18, 90100 Palermo, Italy.ORCID 0000-0002-0786-7294
Angela BonuraIstituto per La Ricerca e l'Innovazione Biomedica-Consiglio Nazionale Delle Ricerche, via Ugo La Malfa 153, 90100 Palermo, Italy.
Laura La PagliaIstituto di Calcolo e Reti ad Alte Prestazioni-Consiglio Nazionale Delle Ricerche, via Ugo La Malfa 153, 90100 Palermo, Italy.
Antonino FiannacaIstituto di Calcolo e Reti ad Alte Prestazioni-Consiglio Nazionale Delle Ricerche, via Ugo La Malfa 153, 90100 Palermo, Italy.ORCID 0000-0002-0114-4984
Massimo La RosaIstituto di Calcolo e Reti ad Alte Prestazioni-Consiglio Nazionale Delle Ricerche, via Ugo La Malfa 153, 90100 Palermo, Italy.
Alfonso UrsoIstituto di Calcolo e Reti ad Alte Prestazioni-Consiglio Nazionale Delle Ricerche, via Ugo La Malfa 153, 90100 Palermo, Italy.
Vincenzo ArizzaDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche-Università di Palermo, via Archirafi 18, 90100 Palermo, Italy.ORCID 0000-0002-8772-7143
Institute for High Performance Computing and Networking · ITUniversity of Palermo · ITInstitute for Biomedical Research and Innovation · IT

Funding

Università degli Studi di Palermo FFR-D15-160403
6 · The paper itself

Abstract

The transforming growth factor-β (TGF-β) family of cytokines performs a multifunctional signaling, which is integrated and coordinated in a signaling network that involves other pathways, such as Wintless, Forkhead box-O (FOXO) and Hedgehog and regulates pivotal functions related to cell fate in all tissues. In the hematopoietic system, TGF-β signaling controls a wide spectrum of biological processes, from immune system homeostasis to the quiescence and self-renewal of hematopoietic stem cells (HSCs). Recently an important role in post-transcription regulation has been attributed to two type of ncRNAs: microRNAs and pseudogenes.

Indexed as

Gene Expression Regulation3' Untranslated RegionsAnimalsCell LineageCionaComputational BiologyForkhead Box Protein O1Hedgehog ProteinsHematopoiesisHigh-Throughput Nucleotide SequencingHomeostasisImmune SystemMicroRNAsPharynxProtein Interaction MappingRNA-Seq3' Untranslated RegionsForkhead Box Protein O1Hedgehog ProteinsMicroRNAsTransforming Growth Factor betaWnt ProteinsascidianFOXOmiRNANGSpseudogenesTGF-βWNT

Identifiers

PMID33800649
PMCPMC8037537
OpenAlexW3147697206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.