ArticleMolecules (Basel, Switzerland)2021
Antimicrobial Activity of Pyrazinamide Coordination Frameworks Synthesized by Mechanochemistry.
Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Bidentate Metal-Binding Motifs in US FDA Approved Small Molecule Drugs.Journal of medicinal chemistry · 2026Review
- A Micro-Configured Multiparticulate Reconstitutable Suspension Powder of Fixed Dose Rifampicin and Pyrazinamide: Optimal Fabrication and In Vitro Quality Evaluation.Pharmaceutics · 2022Article
- Mechanochemistry in Portugal-A Step towards Sustainable Chemical Synthesis.Molecules (Basel, Switzerland) · 2021Review
- Silver(I)-Tazobactam Frameworks with Improved Antimicrobial Activity.Frontiers in chemistry · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The urge for the development of a more efficient antibiotic crystalline forms led us to the disclosure of new antibiotic coordination frameworks of pyrazinamide, a well-known drug used for the treatment of tuberculosis, with some of the novel compounds unravelling improved antimycobacterial activity. Mechanochemistry was the preferred synthetic technique to yield novel compounds, allowing the reproduction of a 1D zinc framework, the synthesis of a novel hydrogen bonding manganese framework, and three new compounds with silver. The structural characterization of the novel forms is presented along with stability studies. The increased antimicrobial activity of the new silver-based frameworks against
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Registered trials
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