Evidence map›Paper›PMID 33800633›Full record

ArticleMaterials (Basel, Switzerland)2021

Controlled Formation of a Protein Corona Composed of Denatured BSA on Upconversion Nanoparticles Improves Their Colloidal Stability.

Samah Shanwar, Liuen Liang, Andrey V Nechaev, Daria K Bausheva, Irina V Balalaeva, Vladimir A Vodeneev, Indrajit Roy, Andrei V Zvyagin, Evgenii L Guryev

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. pH-Dependent HEWL-AuNPs Interactions: Optical Study.Molecules (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samah ShanwarInstitute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 603950 Nizhny Novgorod, Russia.ORCID 0000-0003-0965-437X
Liuen LiangARC Centre of Excellence "Nanoscale BioPhotonics", Department of Physics and Astronomy, Macquarie University, Sydney 2109, Australia.
Andrey V NechaevDepartment of Chemistry and Technology of Biologically Active Compounds, Medical and Organic Chemistry, M.V. Lomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, 119571 Moscow, Russia.
Daria K BaushevaInstitute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 603950 Nizhny Novgorod, Russia.
Irina V BalalaevaInstitute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 603950 Nizhny Novgorod, Russia.ORCID 0000-0002-3245-3907
Vladimir A VodeneevInstitute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 603950 Nizhny Novgorod, Russia.ORCID 0000-0002-3726-5577
Indrajit RoyDepartment of Chemistry, University of Delhi, Delhi 110007, India.
Andrei V ZvyaginInstitute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 603950 Nizhny Novgorod, Russia.ORCID 0000-0001-8799-2257
Evgenii L GuryevInstitute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 603950 Nizhny Novgorod, Russia.ORCID 0000-0002-8845-436X

Funding

BRICS STI Framework Programme Sanction order DST/IMRCD/BRICS/PilotCall2/TherNC/2018 (G)Ministry of Education and Science of the Russian Federation Agreement No. RFMEFI58418X0033
6 · The paper itself

Abstract

In the natural fluidic environment of a biological system, nanoparticles swiftly adsorb plasma proteins on their surface forming a "protein corona", which profoundly and often adversely affects their residence in the systemic circulation in vivo and their interaction with cells in vitro. It has been recognized that preformation of a protein corona under controlled conditions ameliorates the protein corona effects, including colloidal stability in serum solutions. We report on the investigation of the stabilizing effects of a denatured bovine serum albumin (dBSA) protein corona formed on the surface of upconversion nanoparticles (UCNPs). UCNPs were chosen as a nanoparticle model due to their unique photoluminescent properties suitable for background-free biological imaging and sensing. UCNP surface was modified with nitrosonium tetrafluoroborate (NOBF

Indexed as

colloidal stabilitylyophilizationprotein coronaupconversion nanoparticles

Identifiers

PMID33800633
PMCPMC8037850

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.