Evidence map›Paper›PMID 33800589›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Proteomic Expression Profile in Human Temporomandibular Joint Dysfunction.

Andrea Duarte Doetzer, Roberto Hirochi Herai, Marília Afonso Rabelo Buzalaf, Paula Cristina Trevilatto

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06782178 narecruitingnot on this mapstarted 2025, after this paper: background citation

Temporomandibular Joint Arthroscopic Lysis and Lavage Compared to Arthrocentesis in Disc Displacement Without Reduction: a Randomised, Double-blind, Controlled Trial

TypeinterventionalSponsorKarolinska InstitutetRan2025 to 2030Enrolled100ConditionsTemporomandibular Joint Disc Displacement, Temporomandibular Joint Disc Displacement, Without Reduction, Temporomandibular Disorders (TMD)ArmsArthroscopic lysis and lavage, Arthrocentesis/Saline
NCT06782191 narecruitingnot on this mapstarted 2025, after this paper: background citation

Temporomandibular Joint Arthroscopic Lysis and Lavage Compared to Operative Arthroscopy in Disc Displacement With Reduction: a Randomised, Double-blind, Controlled Trial

TypeinterventionalSponsorKarolinska InstitutetRan2025 to 2031Enrolled96ConditionsTemporomandibular Joint Disc Displacement, With Reduction, Temporomandibular Disorders (TMD)ArmsArthroscopic lysis and lavage, Operative arthroscopy
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrea Duarte DoetzerGraduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba 80215-901, Brazil.
Roberto Hirochi HeraiGraduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba 80215-901, Brazil.ORCID 0000-0001-9885-2735
Marília Afonso Rabelo BuzalafDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.ORCID 0000-0002-5985-3951
Paula Cristina TrevilattoGraduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba 80215-901, Brazil.
Pontifícia Universidade Católica do Paraná · BRUniversidade de São Paulo · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico Chamada MCTIC/CNPq Nº 28/2018 - Universal, Process: 426505/2018-2Fundação Araucária grant FA#09/2016
6 · The paper itself

Abstract

Temporomandibular joint dysfunction (TMD) is a multifactorial condition that impairs human's health and quality of life. Its etiology is still a challenge due to its complex development and the great number of different conditions it comprises. One of the most common forms of TMD is anterior disc displacement without reduction (DDWoR) and other TMDs with distinct origins are condylar hyperplasia (CH) and mandibular dislocation (MD). Thus, the aim of this study is to identify the protein expression profile of synovial fluid and the temporomandibular joint disc of patients diagnosed with DDWoR, CH and MD. Synovial fluid and a fraction of the temporomandibular joint disc were collected from nine patients diagnosed with DDWoR (

Indexed as

protein expressiontemporomandibular jointtemporomandibular joint dysfunction

Identifiers

PMID33800589
PMCPMC8066727
OpenAlexW3152152920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.