ArticleBiology2021
Retinal and Choriocapillaris Vascular Changes in Patients Affected by Different Clinical Phenotypes of β-Thalassemia: An Optical Coherence Tomography Angiography Study.
Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Spectral-domain optical coherence tomography characteristics in patients with transfusion-dependent thalassemia.Indian journal of ophthalmology · 2026Article
- The impact of systemic iron overload on retinal and choroidal microcirculation in transfusion-dependent beta-thalassemia patients.BMC ophthalmology · 2026Article
- Determinants of retinal and choriocapillaris microvascular alterations in pediatric β-thalassemia: an OCTA study.International journal of retina and vitreous · 2026Article
- Unusual presentation of tractional retinal detachment in beta thalassemia minor.American journal of ophthalmology case reports · 2023Article
- Does thalassemia truly cause microvascular changes without us noticing? An optical coherence tomography angiography study of the children with beta-thalassemia.International ophthalmology · 2023Article
- Evaluation of parafoveal and peripapillary vascular densities using optical coherence tomography angiography in children with thalassemia major.Therapeutic advances in ophthalmologyArticle
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this cross-sectional study we assessed the vascular alterations in retinal and choriocapillaris perfusion in patients affected by β-thalassemia, by means of optical coherence tomography angiography (OCTA). A total of 124 eyes of 62 patients (mean age 44.74 ± 5.79 years old) affected by β-thalassemia (transfusion dependent thalassemia (TDT), non-transfusion dependent thalassemia (NTDT) and minor) were compared to 40 eyes of twenty healthy subjects. We evaluated the vessel density (VD) in superficial capillary plexus, deep capillary plexus, radial peripapillary capillary, choriocapillaris and the foveal avascular zone area. The TDT group showed a statistically significant reduction in retinal and choriocapillaris VD respect to controls and the other groups (
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