ArticleLife (Basel, Switzerland)2021
Prediction of Insulin Resistance by Modified Triglyceride Glucose Indices in Youth.
Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Article
- Utility of Surrogate Markers for Insulin Resistance: Homeostasis Model Assessment for Insulin Resistance (HOMA-IR) and Triglyceride-Glucose (TyG) Index in Identifying Metabolic Syndrome Among Adults from Resource-limited Settings.TouchREVIEWS in endocrinology · 2026Article
- Review
- TyG index and mild cognitive impairment and dementia: a review of current evidence.Frontiers in aging neuroscience · 2026Review
- Effectiveness of bilingual health education on obesity and dietary behaviors in Mongolian adolescents: a six-month intervention study.Frontiers in public health · 2026Article
- Nonlinear relationship between triglyceride glucose-body mass index and the risk of prediabetes: a multi-center retrospective cohort study.Frontiers in public health · 2026Article
- Association between the triglyceride glucose-waist-to-height ratio and stroke risk among middle-aged and elderly Chinese adults.BMC endocrine disorders · 2025Article
- Utility of TyG-Based Indices for Predicting Insulin Resistance in Turkish Adults: Insights from the TEKHAP Study.Journal of clinical medicine · 2025Article
- Age-related insulin resistance changes in children and adolescents and its impact on the accuracy of diagnosis of metabolic syndrome.Annals of pediatric endocrinology & metabolism · 2025Article
- Prediction Model for Insulin Resistance and Implications for MASLD in Youth: A Novel Marker, the Pediatric Insulin Resistance Assessment Score.Yonsei medical journal · 2025Article
- Identification of pediatric MASLD using insulin resistance indices.JHEP reports : innovation in hepatology · 2025Article
- Association between the combination of the triglyceride-glucose index and obesity-related indices with hyperuricemia among children and adolescents in China.Lipids in health and disease · 2025Article
- Comparison of triglyceride glucose index and other insulin resistance indexes in children with overweight and obesity.BMC endocrine disorders · 2025Article
- Article
- Association between TyG-BMI and early-onset hypertension: evidence from NHANES.Scientific reports · 2025Article
- Comparison of SPISE and METS-IR and Other Markers to Predict Insulin Resistance and Elevated Liver Transaminases in Children and Adolescents.Diabetes & metabolism journal · 2025Article
- Comparison of triglyceride glucose index and modified triglyceride glucose indices in predicting cardiovascular diseases incidence among populations with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study.Cardiovascular diabetology · 2025Article
- Relationship Between the TyGH Index (Based on Triglycerides and HbA1c) and Diabetic Kidney Disease in Patients with Type 2 Diabetes: A Real-World Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Comparison of triglyceride-glucose index and triglyceride-glucose related indexes in predicting cardiovascular disease incidence among populations with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study.Frontiers in endocrinology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The triglyceride glucose (TyG) index, derived from a combination of fasting glucose and triglycerides, has been suggested as a useful marker for insulin resistance (IR), in addition to modified TyG indices that combine obesity parameters. This study investigated the association and utility of TyG and modified TyG indices for IR prediction in youth. Based on the Korea National Health and Nutritional Examination Survey, the data of 3728 youth aged 10-19 years were analyzed. Odds ratios (ORs) and 95% confidence intervals (CIs) of tertiles 2 and 3 for each parameter were calculated and compared with tertile 1 as a reference. To compare the parameters for identifying IR, receiver operating characteristic curves were plotted and the area under the curve (AUC) was calculated. The ORs and 95% CIs for insulin resistance (IR) progressively increased across tertiles of each parameter. Overall, all modified TyG indices presented higher ORs and AUC than the TyG index. The TyG-body mass index standard deviation score showed the largest AUC for IR detection in all subjects. In conclusion, TyG and modified TyG indices could be used as valuable markers for the prediction of IR in youth. Moreover, modified TyG indices had better diagnostic accuracy than the TyG index.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.