Evidence map›Paper›PMID 33800506›Full record

ArticleVaccines2021

Model Comparisons of the Cost Effectiveness of Rubella Vaccination Method in Japanese Adults.

Tomoya Itatani, Ryo Horiike, Hisao Nakai, Kazuya Taira, Chika Honda, Fumie Shirai, Kaoru Konishi

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Tomoya ItataniDivision of Nursing, Faculty of Health Science Institute of Medical, Pharmaceutical and Health Science Kanazawa University, Kanazawa 920-0942, Ishikawa Prefecture, Japan.ORCID 0000-0003-1359-2909
Ryo HoriikeSusaki Regional Welfare and Health Center, Kochi 785-8585, Kochi Prefecture, Japan.
Hisao NakaiNursing Department, Kanazawa Medical University, Uchinada 920-0265, Ishikawa Prefecture, Japan.
Kazuya TairaDepartment of Human Health Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Kyoto Prefecture, Japan.
Chika HondaCenter for Twin Research, Osaka University Graduate School of Medicine, Suita 565-0871, Osaka Prefecture, Japan.
Fumie ShiraiDepartment of Nursing, Morinomiya University of Medical Sciences, Osaka 559-8611, Osaka Prefecture, Japan.
Kaoru KonishiDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita 565-0871, Osaka Prefecture, Japan.
Kanazawa Medical University · JPKanazawa University · JPKyoto University · JPMorinomiya University of Medical Sciences · JPShiga University of Medical Science · JPThe University of Osaka · JP

Funding

Japan Society for the Promotion of Science JP20H04027
6 · The paper itself

Abstract

The number of rubella cases has increased in Japan, especially among adults. Rubella infection in pregnant females can lead to congenital rubella syndrome (CRS). The Japanese government is promoting vaccination to prevent CRS. This study performs a cost-effectiveness analysis of the following four methods: (1) females who wished to become pregnant and partners, with an antibody-titer test; (2) females only, with an antibody-titer test; (3) females and males, without an antibody-titer test; (4) females only, without an antibody-titer test. A decision tree model with a hypothetical cohort of 500 males and 500 females was used for the analysis, and the parameters were obtained from previous studies. The number of avoidances of CRS was defined as the effect. Compared to the case where methods were not implemented, the number of CRS cases that can be prevented by implementing the methods was 0.0115589 by (1) and (3) and 0.0147891 by (2) and (4). The cost effectiveness of (1) to (4) was 287,413,677 JPY, 135,050,529 JPY, 388,524,974 JPY, and 197,744,219 JPY, respectively (1 JPY = 0.00963247 USD). Method (2) was the most cost-effective and did not change by sensitivity analysis. We conclude that the vaccination for females only with an antibody-titer test is recommended.

Indexed as

congenital rubella syndromecost effectivenessrubellavaccine

Identifiers

PMID33800506
PMCPMC8001860
OpenAlexW3134869972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.