Evidence map›Paper›PMID 33800471›Full record

ArticleInternational journal of molecular sciences2021

Prediction of Functional Consequences of Missense Mutations in ANO4 Gene.

Nadine Reichhart, Vladimir M Milenkovic, Christian H Wetzel, Olaf Strauß

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. TMEM16 proteins: CaInternational journal of molecular medicine · 2024
    Review
  4. Article
  5. Review
  6. Polymodal Control of TMEM16x Channels and Scramblases.International journal of molecular sciences · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nadine ReichhartExperimental Ophthalmology, Department of Ophthalmology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität, Berlin Institute of Health, Humboldt-University, 10117 Berlin, Germany.
Vladimir M MilenkovicMolecular Neurosciences, Department of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany.ORCID 0000-0002-6050-8071
Christian H WetzelMolecular Neurosciences, Department of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany.ORCID 0000-0002-5762-0003
Olaf StraußExperimental Ophthalmology, Department of Ophthalmology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität, Berlin Institute of Health, Humboldt-University, 10117 Berlin, Germany.
Humboldt-Universität zu Berlin · DEUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anoctamin (TMEM16) family of transmembrane protein consists of ten members in vertebrates, which act as Ca

Indexed as

Amino Acid SubstitutionAnoctaminsMutation, MissenseSequence Analysis, ProteinHumansProtein StabilityAnoctaminsANO4 geneANO4 proteindisease-associationhomology modelmolecular dynamics simulationprotein stabilityprotein structureSNP

Identifiers

PMID33800471
PMCPMC7962975
OpenAlexW3134299152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.