Evidence map›Paper›PMID 33800415›Full record

Trial reportSensors (Basel, Switzerland)2021

Quantifying Physiological Biomarkers of a Microwave Brain Stimulation Device.

Iqram Hussain, Seo Young, Chang Ho Kim, Ho Chee Meng Benjamin, Se Jin Park

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Iqram HussainCenter for Medical Convergence Metrology, Korea Research Institute of Standards and Science, Daejeon 34113, Korea.ORCID 0000-0002-5183-7631
Seo YoungCenter for Medical Convergence Metrology, Korea Research Institute of Standards and Science, Daejeon 34113, Korea.
Chang Ho KimUNITECH CO., Ltd., Seoul 08289, Korea.
Ho Chee Meng BenjaminAI Research Group, Sewon Intelligence, Ltd., Seoul 04512, Korea.
Se Jin ParkCenter for Medical Convergence Metrology, Korea Research Institute of Standards and Science, Daejeon 34113, Korea.
Korea Research Institute of Standards and Science · KRSuwon Research Institute · KR

Funding

UNITECH CO.,LTD UNITECH_2020
6 · The paper itself

Abstract

Physiological signals are immediate and sensitive to neural and cardiovascular change resulting from brain stimulation, and are considered as a quantifying tool with which to evaluate the association between brain stimulation and cognitive performance. Brain stimulation outside a highly equipped, clinical setting requires the use of a low-cost, ambulatory miniature system. The purpose of this double-blind, randomized, sham-controlled study is to quantify the physiological biomarkers of the neural and cardiovascular systems induced by a microwave brain stimulation (MBS) device. We investigated the effect of an active MBS and a sham device on the cardiovascular and neurological responses of ten volunteers (mean age 26.33 years, 70% male). Electroencephalography (EEG) and electrocardiography (ECG) were recorded in the initial resting-state, intermediate state, and the final state at half-hour intervals using a portable sensing device. During the experiment, the participants were engaged in a cognitive workload. In the active MBS group, the power of high-alpha, high-beta, and low-beta bands in the EEG increased, and the power of low-alpha and theta waves decreased, relative to the sham group. RR Interval and QRS interval showed a significant association with MBS stimulation. Heart rate variability features showed no significant difference between the two groups. A wearable MBS modality may be feasible for use in biomedical research; the MBS can modulate the neurological and cardiovascular responses to cognitive workload.

Indexed as

ElectroencephalographyMicrowavesAdultBiomarkersBrainFemaleHeart RateHumansMaleBiomarkerscognitive workloadmicrowave brain stimulationphysiological biomarkerwearable bioelectronic medicine

Identifiers

PMID33800415
PMCPMC7962824
OpenAlexW3135582951

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.