Evidence map›Paper›PMID 33800279›Full record

ArticleCancers2021

Annexin A1 Is Required for Efficient Tumor Initiation and Cancer Stem Cell Maintenance in a Model of Human Breast Cancer.

Cameron N Johnstone, Yan Tu, Shenna Langenbach, David Baloyan, Andrew D Pattison, Peter Lock, Kara L Britt, Brian D Lehmann, Traude H Beilharz, Matthias Ernst and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cameron N JohnstoneDepartment of Pharmacology and Therapeutics, University of Melbourne, Parkville 3010, Australia.ORCID 0000-0002-6464-8661
Yan TuDepartment of Pharmacology and Therapeutics, University of Melbourne, Parkville 3010, Australia.
Shenna LangenbachDepartment of Pharmacology and Therapeutics, University of Melbourne, Parkville 3010, Australia.
David BaloyanOlivia Newton-John Cancer Research Institute, Heidelberg 3084, Australia.
Andrew D PattisonDepartment of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton 3800, Australia.
Peter LockLa Trobe Bioimaging Platform, La Trobe University, Bundoora 3086, Australia.
Kara L BrittPeter MacCallum Cancer Centre, Cancer Research Division, Melbourne 3000, Australia.
Brian D LehmannVanderbilt-Ingram Cancer Centre, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Traude H BeilharzDepartment of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton 3800, Australia.ORCID 0000-0002-8942-9502
Matthias ErnstOlivia Newton-John Cancer Research Institute, Heidelberg 3084, Australia.
Robin L AndersonSir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3000, Australia.ORCID 0000-0002-6841-7422
Alastair G StewartDepartment of Pharmacology and Therapeutics, University of Melbourne, Parkville 3010, Australia.

Funding

National Health and Medical Research Council (Australia) APP1020280National Health and Medical Research Council (Australia) APP1023185National Health and Medical Research Council (Australia) APP1042848National Health and Medical Research Council (Australia) APP1050384National Health and Medical Research Council (Australia) APP1128250
6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) has a poor outcome compared to other breast cancer subtypes, and new therapies that target the molecular alterations driving tumor progression are needed. Annexin A1 is an abundant multi-functional Ca

Indexed as

allograftAnnexin A1breast cancermouse modelxenograft

Identifiers

PMID33800279
PMCPMC7962654

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.