Evidence map›Paper›PMID 33800248›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Synthesis, Characterization and Safety Evaluation of Sericin-Based Hydrogels for Controlled Delivery of Acyclovir.

Moawia M Al-Tabakha, Shujaat Ali Khan, Akram Ashames, Hamid Ullah, Kaleem Ullah, Ghulam Murtaza, Nageeb Hassan

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Moawia M Al-TabakhaCollege of Pharmacy and Health Sciences, Ajman University, P.O. Box 346, Ajman, United Arab Emirates.ORCID 0000-0001-6425-3582
Shujaat Ali KhanDepartment of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.
Akram AshamesCollege of Pharmacy and Health Sciences, Ajman University, P.O. Box 346, Ajman, United Arab Emirates.ORCID 0000-0003-3124-8802
Hamid UllahDepartment of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.
Kaleem UllahHamdard Institute of Pharmaceutical Sciences, Hamdard University, Islamabad Campus, Islamabad 44000, Pakistan.
Ghulam MurtazaDepartment of Pharmacy, COMSATS University Islamabad, Lahore Campus, Lahore 54000, Pakistan.
Nageeb HassanCollege of Pharmacy and Health Sciences, Ajman University, P.O. Box 346, Ajman, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional formulations of antiviral drug acyclovir have various limitations such as low bioavailability. The current study was aimed at developing polymeric matrices for the controlled delivery of acyclovir using sericin as polymer and acrylic acid (AA) as a monomer. The free radical polymerization technique was used for hydrogel formulation. Briefly, sericin was chemically cross-linked with acrylic acid.

Indexed as

free radical polymerizationgraftingkinetic modelsmonomeroral tolerabilitypH-responsiveswelling ratio

Identifiers

PMID33800248
PMCPMC8000570

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.