Evidence map›Paper›PMID 33800183›Full record

ReviewCancers2021

Nathalie Olympios, Vianney Gilard, Florent Marguet, Florian Clatot, Frédéric Di Fiore, Maxime Fontanilles

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 5 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 5 syntheses or guidelines pooled it, 97 citations in OpenAlex.

  1. Pooled it
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  5. Pooled it
  6. Trial
  7. Article
  8. Review
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  11. Review
  12. Review
  13. The Role of CRISPR and Its Therapeutic Applications in Glioblastoma.International journal of molecular sciences · 2026
    Review
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  16. Article
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  20. Review

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Nathalie OlympiosCancer Centre Henri Becquerel, Department of Medical Oncology, Rue d'Amiens, 76000 Rouen, France.ORCID 0000-0002-3943-3730
Vianney GilardNeurosurgery Department, Rouen University Hospital, 1 rue de Germont, 76000 Rouen, France.
Florent MarguetDepartment of Pathology, INSERM U1245, Normandie Univ, UNIROUEN and Rouen University Hospital, Normandy Centre for Genomic and Personalized Medicine, 76000 Rouen, France.ORCID 0000-0003-4350-7349
Florian ClatotCancer Centre Henri Becquerel, Department of Medical Oncology, Rue d'Amiens, 76000 Rouen, France.
Frédéric Di FioreCancer Centre Henri Becquerel, Department of Medical Oncology, Rue d'Amiens, 76000 Rouen, France.
Maxime FontanillesCancer Centre Henri Becquerel, Department of Medical Oncology, Rue d'Amiens, 76000 Rouen, France.
Inserm · FRLaboratoire National Henri Becquerel · FRUniversité de Rouen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma, the most frequent and aggressive primary malignant tumor, often presents with alterations in the telomerase reverse transcriptase promoter. Telomerase is responsible for the maintenance of telomere length to avoid cell death. Telomere lengthening is required for cancer cell survival and has led to the investigation of telomerase activity as a potential mechanism that enables cancer growth. The aim of this systematic review is to provide an overview of the available data concerning

Indexed as

glioblastomatelomerase inhibitionTERT

Identifiers

PMID33800183
PMCPMC7962450
OpenAlexW3135451623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.