Evidence map›Paper›PMID 33800155›Full record

ReviewDiagnostics (Basel, Switzerland)2021

Arrhythmic Mitral Valve Prolapse: Introducing an Era of Multimodality Imaging-Based Diagnosis and Risk Stratification.

Deni Kukavica, Marco Guglielmo, Andrea Baggiano, Giuseppe Muscogiuri, Laura Fusini, Manuela Muratori, Gloria Tamborini, Valentina Mantegazza, Alessandro Trancuccio, Carlo Arnò and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Mitral Annular Disjunction: A Roadmap for the Surgeon.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2026
    Review
  2. Review
  3. Review
  4. Mitral annular disjunction in out-of-hospital cardiac arrest patients-a retrospective cardiac MRI study.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Article
  5. Review
  6. Article
  7. Review
  8. Additional value of cardiac magnetic resonance feature tracking parameters for the evaluation of the arrhythmic risk in patients with mitral valve prolapse.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  9. Strain Imaging and Ventricular Arrhythmia.Diagnostics (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. International journal of molecular sciences · 2022
    Article
  14. Article
  15. Review
  16. Two Cases of Arrhythmic Mitral Valve Prolapse: Evil Has Many Faces.The Journal of innovations in cardiac rhythm management · 2022
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Deni KukavicaMolecular Cardiology, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy.ORCID 0000-0002-7152-5934
Marco GuglielmoDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Andrea BaggianoDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0002-8261-4529
Giuseppe MuscogiuriDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Laura FusiniDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0003-0309-6231
Manuela MuratoriDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Gloria TamboriniDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Valentina MantegazzaDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0002-0696-1625
Alessandro TrancuccioMolecular Cardiology, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy.ORCID 0000-0002-2181-8245
Carlo ArnòMolecular Cardiology, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy.
Andrea MazzantiMolecular Cardiology, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy.
Mauro PepiDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0003-2524-6288
Silvia Giuliana PrioriMolecular Cardiology, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy.
Gianluca PontoneDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0002-1339-6679
Centro Cardiologico Monzino · ITUniversity of Pavia · ITIstituti Clinici Scientifici Maugeri · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitral valve prolapse is a common cardiac condition, with an estimated prevalence between 1% and 3%. Most patients have a benign course, but ever since its initial description mitral valve prolapse has been associated to sudden cardiac death. Although the causal relationship between mitral valve prolapse and sudden cardiac death has never been clearly demonstrated, different factors have been implicated in arrhythmogenesis in patients with mitral valve prolapse. In this work, we offer a comprehensive overview of the etiology and the genetic background, epidemiology, pathophysiology, and we focus on the state-of-the-art imaging-based diagnosis of mitral valve prolapse. Going beyond the classical, well-described clinical factors, such as young age, female gender and auscultatory findings, we investigate multimodality imaging features, such as alterations of anatomy and function of the mitral valve and its leaflets, the structural and contractile anomalies of the myocardium, all of which have been associated to sudden cardiac death.

Indexed as

arrhythmiacardiovascular magnetic resonanceechocardiographymitral valve prolapsemultimodality imagingrisk factorssudden cardiac death

Identifiers

PMID33800155
PMCPMC7999774
OpenAlexW3135841076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.