ArticleAnimals : an open access journal from MDPI2021
Total and Differential Cell Counts as a Tool to Identify Intramammary Infections in Cows after Calving.
Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- Dysregulated Efferocytosis and Immune Microenvironment in High Somatic Cell Count Dairy Cows.Journal of animal physiology and animal nutrition · 2026Article
- Internal Teat Sealant as an Alternative to Intramammary Antibiotics at Dry-Off in Low-Risk Dairy Cows: Effects on Udder Health, Milk Yield, Antimicrobial Use, and Economic Outcomes.Animals : an open access journal from MDPI · 2026Article
- Integrative Multivariate Analysis of Milk Biomarkers, Productive Performance, and Animal Welfare Indicators in Dairy Cows.Animals : an open access journal from MDPI · 2025Article
- Selective Dry Cow Therapy in Modern Dairy Management: Balancing Udder Health and Antimicrobial Stewardship.Veterinary sciences · 2025Review
- Machine Learning Approach for Early Lactation Mastitis Diagnosis Using Total and Differential Somatic Cell Counts.Animals : an open access journal from MDPI · 2025Article
- Ginsenoside Rg1 Alleviates Blood-Milk Barrier Disruption in Subclinical Bovine Mastitis by Regulating Oxidative Stress-Induced Excessive Autophagy.Antioxidants (Basel, Switzerland) · 2024Article
- Extracellular vesicle miRNome during subclinical mastitis in dairy cows.Veterinary research · 2024Article
- Development of a lateral flow device for rapid simultaneous multiple detections of some common bacterial causes of bovine mastitis.Journal of advanced veterinary and animal research · 2023Article
- Early Milk Total and Differential Cell Counts as a Diagnostic Tool to Improve Antimicrobial Therapy Protocols.Animals : an open access journal from MDPI · 2023Article
- Delayed First Milking in Unassisted Overnight Calving Did Not Affect the Quality of Colostrum but Influenced Serum Brix Refractometry in Holstein Calves at Two Days of Life.Animals : an open access journal from MDPI · 2022Article
- MALDI-TOF mass spectrometry profiling of bovine skim milk for subclinical mastitis detection.Frontiers in veterinary science · 2022Article
- Relationship between total and differential quarter somatic cell counts at dry-off and early lactation.PloS one · 2022Article
- Assessment of Sensitivity and Profitability of an Intravaginal Sensor for Remote Calving Prediction in Dairy Cattle.Sensors (Basel, Switzerland) · 2021Article
- Milk Somatic Cell Count and Polymorphonuclear Cells in Healthy Quarters of Cows That Underwent Blanket and Selective Dry Therapy: An Italian Case Study.Veterinary sciences · 2021Article
- Aptamer-based diagnostic and therapeutic approaches in animals: Current potential and challenges.Saudi journal of biological sciences · 2021Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Milk differential somatic cells count (DSCC), made possible under field conditions by the recent availability of a high-throughput milk analyzer may represent an improvement in mastitis diagnosis. While an increasing number of studies reports data on DSCC on individual cow samples, very few concerns DSCC from quarter milk samples. This paper reports for the first time the results of a retrospective study aiming to assess the performance of total (SCC), DSCC, and a novel calculated marker (PLCC) measured on quarter milk samples as a method to identify cows at risk for intramammary infection (IMI) in the first 30 days after calving. Overall, 14,586 valid quarter milk samples (3658 cows) taken in the first 30 days of lactation were considered. Quarters with major pathogens (MP) IMI, as expected, showed significantly higher means for SCC, DSCC, and PLCC. The accuracy, sensitivity, and specificity of the diagnosis based on different cut-offs calculated by ROC analysis are relatively close among DSCC, PLCC, and SCC (up to cut-off of 200,000 cells/mL). However, decision-tree analysis which includes the costs of analysis, but also the costs of the actions taken after test results showed as PLCC has the lowest cost among the three markers, and PLCC and SCC are cost effective when MP prevalence is higher than 6-10%. This diagnostic approach is of high interest particularly when selective dry cow therapy is applied to improve animal health at the herd level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.