Evidence map›Paper›PMID 33800005›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Temperate Zone Plant Natural Products-A Novel Resource for Activity against Tropical Parasitic Diseases.

Hamza Hameed, Elizabeth F B King, Katerina Doleckova, Barbara Bartholomew, Jackie Hollinshead, Haddijatou Mbye, Imran Ullah, Karen Walker, Maria Van Veelen, Somaia Saif Abou-Akkada and 3 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 6 countries.

Hamza HameedCentre for Applied Entomology and Parasitology, Keele University, Staffordshire ST5 5BG, UK.
Elizabeth F B KingCentre for Applied Entomology and Parasitology, Keele University, Staffordshire ST5 5BG, UK.ORCID 0000-0001-7452-4518
Katerina DoleckovaCentre for Applied Entomology and Parasitology, Keele University, Staffordshire ST5 5BG, UK.
Barbara BartholomewPhytoQuest Limited, Aberystwyth SY23 3EB, UK.
Jackie HollinsheadPhytoQuest Limited, Aberystwyth SY23 3EB, UK.
Haddijatou MbyeCentre for Applied Entomology and Parasitology, Keele University, Staffordshire ST5 5BG, UK.
Imran UllahCentre for Applied Entomology and Parasitology, Keele University, Staffordshire ST5 5BG, UK.ORCID 0000-0003-1432-1705
Karen WalkerSchool of Life Sciences, Keele University, Staffordshire ST5 5BG, UK.
Maria Van VeelenCentre for Applied Entomology and Parasitology, Keele University, Staffordshire ST5 5BG, UK.ORCID 0000-0002-4295-6364
Somaia Saif Abou-AkkadaFaculty of Veterinary Medicine, Alexandria University, Alexandria, Abis 10, Egypt.
Robert J NashPhytoQuest Limited, Aberystwyth SY23 3EB, UK.
Paul D HorrocksCentre for Applied Entomology and Parasitology, Keele University, Staffordshire ST5 5BG, UK.
Helen P PriceCentre for Applied Entomology and Parasitology, Keele University, Staffordshire ST5 5BG, UK.ORCID 0000-0003-1537-4390
Keele University · GBAberystwyth University · GBAlexandria University · EGHarvard University · USMRC Unit the Gambia · GMUniversity of Mosul · IQ

Funding

British Society for Antimicrobial Chemotherapy BSAC-2018-0004Higher Committee for Education Development in Iraq (HCED) award N/AHigh Value Chemicals from Plants (BBSRC) N/AMedical Research Council MR/P011241/1Newton Fund 261876735
6 · The paper itself

Abstract

The use of plant-derived natural products for the treatment of tropical parasitic diseases often has ethnopharmacological origins. As such, plants grown in temperate regions remain largely untested for novel anti-parasitic activities. We describe here a screen of the PhytoQuest Phytopure library, a novel source comprising over 600 purified compounds from temperate zone plants, against in vitro culture systems for

Indexed as

African trypanosomiasisdrug discoveryleishmaniasismalarianatural productsneglected tropical diseasesSurratemperate zone

Identifiers

PMID33800005
PMCPMC7998250
OpenAlexW3134685002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.