ReviewPolymers2021
Bond Strength of Universal Adhesives to Dentin: A Systematic Review and Meta-Analysis.
Review in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effect of Dentin Biomodification on the Survival of Resin Composite Restorations: An Umbrella Review.International dental journal · 2026Pooled it
- Biomimetic Remineralization Strategies for Dentin Bond Stability-Systematic Review and Network Meta-Analysis.International journal of molecular sciences · 2025Pooled it
- Pooled it
- Pooled it
- 24-Month clinical evaluation of cervical restorations bonded using radio-opaque universal adhesive compared to conventional universal adhesive in carious cervical lesions: A randomized clinical trial.Scientific reports · 2025Trial
- Bond Strengths of Universal Adhesives to Dentin Contaminated with a Hemostatic Agent.The journal of adhesive dentistry · 2022Trial
- Post-and-Core Buildup Techniques with Short Fiber-Reinforced Composite and Polyethylene Fiber: In Vitro Evaluation of the Fracture Load and Mode of Failure.Materials (Basel, Switzerland) · 2026Article
- Comparison of Four Universal Adhesive Protocols for the Internal Adaptation of Composite Restorations in Primary Teeth: An In Vitro Micro-CT Study.Materials (Basel, Switzerland) · 2026Article
- Effect of diode laser on micro-tensile bond strength of hybrid ceramic restorations to dentin using one-step and two-step self-etch adhesives: in vitro study.BMC oral health · 2026Article
- Three-Dimensional Micro-CT Assessment of Radiopacity and Intra-Cavity Distribution of Universal Adhesives.Materials (Basel, Switzerland) · 2026Article
- Commercial trends in universal adhesive evolution: updated formulations do not consistently improve dentin bond strength after aging compared with predecessors and a multistep reference.BMC oral health · 2026Article
- Microtensile bond strength and dentin-adhesive interface of universal adhesives before and after artificial aging: an in vitro study.Scientific reports · 2026Article
- Does Air Abrasion of Dentin Affect the Bonding Performance of Different Universal Adhesives?Journal of dentistry (Shiraz, Iran) · 2026Article
- The impact of three desensitizing materials on the shear strength between composite resin and dentin: an in-vitro study.BMC oral health · 2025Article
- Effect of Etching Mode on the Dentin Bond Durability of Universal Adhesives.The journal of adhesive dentistry · 2025Article
- Effect of short dentin etching and water storage on bonding of resin composite to dentin with universal and two-step self-etch adhesive systems.Scientific reports · 2025Article
- Review
- Effect of the double-application of one-step universal adhesives on bonding strength to bur-cut enamel.BMC oral health · 2025Article
- Effect of Remineralization Products on the Microtensile Strength of Universal Dentin Bonding Systems.Dentistry journal · 2025Article
- Physico-Chemical Properties and Performance of Functional Monomers Used in Contemporary Dental Adhesive Technology.The journal of adhesive dentistry · 2025Review
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Currently, the availability of a wide variety of universal adhesives makes it difficult for clinicians to choose the correct system for specific bonding situations to dentin substrate. This study aimed to determine whether there are any alternative techniques or additional strategies available to enhance the bond strength of universal adhesives to dentin through a systematic review and meta-analysis. Two reviewers executed a literature search up to September 2020 in four electronic databases: PubMed, ISI Web of Science, Scopus, and EMBASE. Only in vitro studies that reported the dentin bond strength of universal adhesives using additional strategies were included. An analysis was carried out using Review Manager Software version 5.3.5 (The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark). The methodological quality of each in vitro study was assessed according to the parameters of a previous systematic. A total of 5671 potentially relevant studies were identified. After title and abstract examination, 74 studies remained in systematic review. From these, a total of 61 studies were included in the meta-analysis. The bond strength of universal adhesives to dentin was improved by the use of one of the following techniques: Previous application of matrix metalloproteinases (MMP) inhibitors (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.