Evidence map›Paper›PMID 33799921›Full record

ArticlePathogens (Basel, Switzerland)2021

Impact of Annual Albendazole versus Four-Monthly Test-and-Treat Approach of Intestinal Parasites on Children Growth-A Longitudinal Four-Arm Randomized Parallel Trial during Two Years of a Community Follow-Up in Bengo, Angola.

Carolina Gasparinho, Aguinaldo Kanjungo, Félix Zage, Isabel Clemente, Ana Santos-Reis, Miguel Brito, José Carlos Sousa-Figueiredo, Filomeno Fortes, Luzia Gonçalves

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Carolina GasparinhoCentro de Investigação em Saúde de Angola (CISA), Rua Direita de Caxito, Caxito, Angola.ORCID 0000-0002-0095-6155
Aguinaldo KanjungoCentro de Investigação em Saúde de Angola (CISA), Rua Direita de Caxito, Caxito, Angola.
Félix ZageCentro de Investigação em Saúde de Angola (CISA), Rua Direita de Caxito, Caxito, Angola.
Isabel ClementeCentro de Investigação em Saúde de Angola (CISA), Rua Direita de Caxito, Caxito, Angola.
Ana Santos-ReisGlobal Health and Tropical Medicine (GHTM), Instituto de Higiene e Medicina Tropical (IHMT), Universidade Nova de Lisboa (UNL), 1349-008 Lisbon, Portugal.
Miguel BritoCentro de Investigação em Saúde de Angola (CISA), Rua Direita de Caxito, Caxito, Angola.ORCID 0000-0001-6394-658X
José Carlos Sousa-FigueiredoCentro de Investigação em Saúde de Angola (CISA), Rua Direita de Caxito, Caxito, Angola.
Filomeno FortesGlobal Health and Tropical Medicine (GHTM), Instituto de Higiene e Medicina Tropical (IHMT), Universidade Nova de Lisboa (UNL), 1349-008 Lisbon, Portugal.
Luzia GonçalvesGlobal Health and Tropical Medicine (GHTM), Instituto de Higiene e Medicina Tropical (IHMT), Universidade Nova de Lisboa (UNL), 1349-008 Lisbon, Portugal.ORCID 0000-0002-9710-1945
Universidade Nova de Lisboa · PTAgostinho Neto University · AOInstituto Politécnico de Lisboa · PTUniversity of Lisbon · PT

Funding

CISA (Camões, Institute of Cooperation and Language, Portugal NAFundação Calouste Gulbenkian 212008Fundação para a Ciência e a Tecnologia SFRH/BD/91566/2012, UID/MAT/00006/2019, and UID/Muli/04413/2019Government of Bengo Province; Angolan Ministry of Health - MINSA) and the National Malaria Control Program, Angola NA
6 · The paper itself

Abstract

Malnutrition and intestinal parasites continue to have serious impacts on growth and cognitive development of children in Angola. A longitudinal four-arm randomized parallel trial was conducted to investigate if deworming with a single annual dose of albendazole (annual-ALB) or a four-monthly test-and-treat (4TT) intestinal parasites approach at individual or household levels improve nutritional outcomes of pre-school children in Bengo province. Children with intestinal parasites (n = 121) were randomly assigned (1:1:1:1) to arm A1: annual-ALB*individual level; A2: annual-ALB*household level; A3: 4TT*individual; and A4: 4TT*household level. At baseline, 4, 8, 12, 16, 20, and 24 months of follow-up, growth was assessed by height, weight, height-for-age, weight-for-height, weight-for-age, and mid-upper arm circumference. Intention-to-treat analysis was done using non-parametric approach, mixed effect models, and generalized estimating equations (GEE). Initially, 57% and 26% of the children were infected by

Indexed as

deworminggrowthintestinal parasiteslongitudinalstuntingZ-score

Identifiers

PMID33799921
PMCPMC8001871
OpenAlexW3134035752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.