Evidence map›Paper›PMID 33799854›Full record

ReviewMedicina (Kaunas, Lithuania)2021

Renal Morphology in Coronavirus Disease: A Literature Review.

Patrick de Oliveira, Kaile Cunha, Precil Neves, Monique Muniz, Giuseppe Gatto, Natalino Salgado Filho, Felipe Guedes, Gyl Silva

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Patrick de OliveiraNephrology Service, Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, Natal 59066-230, RN, Brazil.ORCID 0000-0003-3773-1969
Kaile CunhaUniversity Hospital of Federal University of Maranhão, São Luis 65020-070, MA, Brazil.
Precil NevesNephrology Division, University of São Paulo Medical School, São Paulo 05403-000, SP, Brazil.ORCID 0000-0003-1089-6763
Monique MunizUniversity Hospital of Federal University of Maranhão, São Luis 65020-070, MA, Brazil.ORCID 0000-0002-4550-2341
Giuseppe GattoNephrology Service, University Hospital of Brasília, Brasília 70840-901, DF, Brazil.ORCID 0000-0001-6587-5949
Natalino Salgado FilhoUniversity Hospital of Federal University of Maranhão, São Luis 65020-070, MA, Brazil.
Felipe GuedesNephrology Service, Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, Natal 59066-230, RN, Brazil.
Gyl SilvaPatology Department, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Universidade Federal do Maranhão · BRUniversidade de São Paulo · BRUniversidade Federal do Rio Grande do Norte · BRHospital Universitário de Brasília · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal biopsy is useful to better understand the histological pattern of a lesion (glomerular, tubulointerstitial, and vascular) and the pathogenesis that leads to kidney failure. The potential impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the kidneys is still undetermined, and a variety of lesions are seen in the kidney tissue of coronavirus disease patients. This review is based on the morphological findings of patients described in case reports and a series of published cases. A search was conducted on MEDLINE and PubMed of case reports and case series of lesions in the presence of non-critical infection by SARS-CoV-2 published until 15/09/2020. We highlight the potential of the virus directly influencing the damage or the innate and adaptive immune response activating cytokine and procoagulant cascades, in addition to the genetic component triggering glomerular diseases, mainly collapsing focal segmental glomerulosclerosis, tubulointerstitial, and even vascular diseases. Kidney lesions caused by SARS-CoV-2 are frequent and have an impact on morbidity and mortality; thus, studies are needed to assess the morphological kidney changes and their mechanisms and may help define their spectrum and immediate or long-term impact.

Indexed as

Acute Kidney InjuryAdaptive ImmunityArteriosclerosisCOVID-19CytokinesGlomerulonephritisGlomerulonephritis, IGAGlomerulosclerosis, Focal SegmentalHumansImmunity, InnateInfarctionKidneyKidney Cortex NecrosisNephritis, InterstitialNephrosis, LipoidRhabdomyolysisCytokinescoronavirusCOVID-19renal biopsyrenal morphology

Identifiers

PMID33799854
PMCPMC7998438
OpenAlexW3136233926

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.