Evidence map›Paper›PMID 33799840›Full record

ArticleCells2021

Hydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents.

Li Xiao, Nobuhiko Miwa

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Li XiaoDepartment of Pharmacology, School of Life Dentistry at Tokyo, Nippon Dental University, Tokyo 102-8159, Japan.ORCID 0000-0002-3053-4930
Nobuhiko MiwaFaculty of Life Sciences, Prefectural University of Hiroshima, Hiroshima 727-0023, Japan.ORCID 0000-0003-0136-5952
Nippon Dental University · JPPrefectural University of Hiroshima · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive oxygen species (ROS)-induced oxidative stress in adipose tissue is associated with inflammation and the development of obesity-related metabolic disorders. The aim of this study is to investigate the effects of hydrogen nano-bubble water (HW) on ROS generation, adipogenesis, and interleukin-6 (IL-6) secretion in hydrogen peroxide (H

Indexed as

AdipocytesAdipogenesisAnimalsAnti-Inflammatory AgentsAntioxidantsCoculture TechniquesHumansHydrogenHydrogen PeroxideInterleukin-6KeratinocytesMiceNanoparticlesOxidative StressReactive Oxygen SpeciesSignal TransductionAnti-Inflammatory AgentsAntioxidantsHydrogenHydrogen PeroxideInterleukin-6interleukin-6, mouseReactive Oxygen SpeciesTetradecanoylphorbol AcetateWateradipogenesisadipose equivalentshydrogen peroxidehydrogen-rich waterIL-6inflammationmetabolic disordersnano-bubblesphorbol 12-myristate 13-acetatereactive oxygen species

Identifiers

PMID33799840
PMCPMC7998368
OpenAlexW3135478870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.