Evidence map›Paper›PMID 33799830›Full record

ArticleBiomolecules2021

Lipidomic Signatures for Colorectal Cancer Diagnosis and Progression Using UPLC-QTOF-ESI

Claudiu Răchieriu, Dan Tudor Eniu, Emil Moiş, Florin Graur, Carmen Socaciu, Mihai Adrian Socaciu, Nadim Al Hajjar

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Crosstalk between mFrontiers in immunology · 2026
    Review
  5. Article
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  7. Lipids: Driving Forces in the Underlying Biology of Carcinogenesis.ACS pharmacology & translational science · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Claudiu RăchieriuSurgery Department, County Hospital Alba, 510118 Alba Iulia, Romania.
Dan Tudor EniuOncology Department, Iuliu Hațieganu University of Medicine and Pharmacy, 400015 Cluj-Napoca, Romania.ORCID 0000-0002-6988-2828
Emil MoişIuliu Hatieganu University of Medicine and Pharmacy, Regional Institute of Gastroenterology and Hepatology "Octavian Fodor", 400015 Cluj-Napoca, Romania.ORCID 0000-0002-2972-3777
Florin GraurIuliu Hatieganu University of Medicine and Pharmacy, Regional Institute of Gastroenterology and Hepatology "Octavian Fodor", 400015 Cluj-Napoca, Romania.
Carmen SocaciuUniversity of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.ORCID 0000-0002-7352-5057
Mihai Adrian SocaciuIuliu Hatieganu University of Medicine and Pharmacy, Regional Institute of Gastroenterology and Hepatology "Octavian Fodor", 400015 Cluj-Napoca, Romania.
Nadim Al HajjarIuliu Hatieganu University of Medicine and Pharmacy, Regional Institute of Gastroenterology and Hepatology "Octavian Fodor", 400015 Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · ROUniversity of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolomics coupled with bioinformatics may identify relevant biomolecules such as putative biomarkers of specific metabolic pathways related to colorectal diagnosis, classification and prognosis. This study performed an integrated metabolomic profiling of blood serum from 25 colorectal cancer (CRC) cases previously classified (Stage I to IV) compared with 16 controls (disease-free, non-CRC patients), using high-performance liquid chromatography and mass spectrometry (UPLC-QTOF-ESI

Indexed as

Disease ProgressionLipidomicsSpectrometry, Mass, Electrospray IonizationAgedAlgorithmsArea Under CurveBiomarkersChromatography, High Pressure LiquidColorectal NeoplasmsDiscriminant AnalysisFemaleHumansLeast-Squares AnalysisMaleMetabolomeMiddle AgedBiomarkersbiomoleculescolorectal cancerhigh-performance liquid chromatographymass spectrometryMetaboanalystmetabolomicsputative biomarkers

Identifiers

PMID33799830
PMCPMC8035671
OpenAlexW3133926915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.