Evidence map›Paper›PMID 33799756›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Effects of Essential Oils and Some Constituents from Ingredients of Anti-Cellulite Herbal Compress on 3T3-L1 Adipocytes and Rat Aortae.

Ngamrayu Ngamdokmai, Tamkeen Urooj Paracha, Neti Waranuch, Krongkarn Chootip, Wudtichai Wisuitiprot, Nungruthai Suphrom, Kamonlak Insumrong, Kornkanok Ingkaninan

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Advances in essential oils for metabolic diseases.Frontiers in endocrinology · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Essential Oil of Carvone ChemotypeCurrent issues in molecular biology · 2022
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ngamrayu NgamdokmaiCentre of Excellence in Cannabis Research, Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.
Tamkeen Urooj ParachaDepartment of Pharmacology, Faculty of Pharmacy, Hamdard University, Main Campus, Karachi 74600, Pakistan.
Neti WaranuchCosmetics and Natural Products Research Center and Center of Excellence for Innovation in Chemistry, Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65000, Thailand.
Krongkarn ChootipDepartment of Physiology, Faculty of Medical Sciences, Naresuan University, Phitsanulok 65000, Thailand.ORCID 0000-0001-6973-158X
Wudtichai WisuitiprotDepartment of Thai Traditional Medicine, Sirindhorn College of Public Health, Phitsanulok 65130, Thailand.ORCID 0000-0001-8072-1382
Nungruthai SuphromDepartment of Chemistry, Faculty of Science and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.
Kamonlak InsumrongDepartment of Chemistry, Faculty of Science and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.
Kornkanok IngkaninanCentre of Excellence in Cannabis Research, Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.ORCID 0000-0002-4415-8489
Naresuan University · THHamdard University · PKSirindhorn College of Public Health · TH

Funding

National Research Council of Thailand DBG6080005, IRN61W0005Royal Golden Jubilee (RGJ) Ph.D. Programme 0008/2560Thailand Center of Excellence for Life Sciences TC-A2/62
6 · The paper itself

Abstract

Cellulite is associated with a complex array of adipocytes under the skin and vascular system. A herbal compress that was previously developed was proven to have an anti-cellulite effect in healthy volunteers within 2 weeks of treatment. However, its mechanism and ingredients responsible for reducing cellulite were not known. The purpose of this study was to investigate the activity of eight essential oils in, and two water extracts from, the ingredients of the herbal compress together with nine monoterpenoid constituents on the 3T3-L1 adipocytes. The vasodilatory effect on rat aortae was also studied. The adipocytes were induced by dexamethasone, 3-isobutyl-1-methylxanthine and insulin. At all concentrations tested, all essential oils, water extracts and their monoterpenoid constituents significantly inhibited lipid accumulation activity (

Indexed as

adipogenesiscelluliteessential oillipolysismonoterpenesThai herbal compressvasorelaxation

Identifiers

PMID33799756
PMCPMC7999046
OpenAlexW3133676544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.