Evidence map›Paper›PMID 33799739›Full record

ArticleInternational journal of molecular sciences2021

Subunits of the PBAP Chromatin Remodeler Are Capable of Mediating Enhancer-Driven Transcription in

Yulii V Shidlovskii, Oleg V Bylino, Alexander V Shaposhnikov, Zaur M Kachaev, Lyubov A Lebedeva, Valeria V Kolesnik, Diego Amendola, Giovanna De Simone, Nadia Formicola, Paul Schedl and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Medical science pulse · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 4 countries.

Yulii V ShidlovskiiDepartment of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.ORCID 0000-0002-3643-9889
Oleg V BylinoDepartment of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.ORCID 0000-0002-8399-6194
Alexander V ShaposhnikovDepartment of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Zaur M KachaevDepartment of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.ORCID 0000-0002-3866-0798
Lyubov A LebedevaDepartment of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Valeria V KolesnikDepartment of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Diego AmendolaDepartment of Biology, Università di Napoli Federico II, 80138 Naples, Italy.
Giovanna De SimoneDepartment of Biology, Università di Napoli Federico II, 80138 Naples, Italy.
Nadia FormicolaInstitute of Research on Terrestrial Ecosystems (IRET) National Research Council (CNR), 05010 Porano, Italy.ORCID 0000-0002-2039-1323
Paul SchedlDepartment of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Filomena Anna DigilioInstitute of Research on Terrestrial Ecosystems (IRET) National Research Council (CNR), 05010 Porano, Italy.ORCID 0000-0002-9342-3760
Ennio GiordanoDepartment of Biology, Università di Napoli Federico II, 80138 Naples, Italy.ORCID 0000-0003-3870-4006
Institute of Gene Biology · RUUniversity of Naples Federico II · ITCentre National de la Recherche Scientifique · FRNational Research Council · ITPrinceton University · USRoma Tre University · ITSechenov University · RUSirius University of Science and Technology · RU

Funding

Genetic regulatory mechanism in development and differentiationR35GM126975 · NIGMS · PRINCETON UNIVERSITY · PI SCHEDL, PAUL D · 2018 to 2022
$3.0M
Italian POR "BioIndustrial Processess" (BIP)NIGMS NIH HHS R35 GM126975Russian Foundation for Basic Research 19-34-51003
6 · The paper itself

Abstract

The chromatin remodeler SWI/SNF is an important participant in gene activation, functioning predominantly by opening the chromatin structure on promoters and enhancers. Here, we describe its novel mode of action in which SWI/SNF factors mediate the targeted action of an enhancer. We studied the functions of two signature subunits of PBAP subfamily, BAP170 and SAYP, in

Indexed as

Transcription, GeneticAnimalsAnimals, Genetically ModifiedChromatin Assembly and DisassemblyDrosophila melanogasterDrosophila ProteinsEnhancer Elements, GeneticFluorescent Antibody Technique, IndirectHumansIn Situ HybridizationModels, GeneticPromoter Regions, GeneticProtein SubunitsTranscriptional ActivationTranscription FactorsBAP170 protein, DrosophilaDrosophila Proteinse(y)3 protein, DrosophilaProtein SubunitsTranscription Factorschromatin remodelingenhancerPBAPpromoterSWI/SNF

Identifiers

PMID33799739
PMCPMC7999800
OpenAlexW3133854550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.