ArticleAnimals : an open access journal from MDPI2021
Red Cell Distribution Width Has a Negative Prognostic Role in Dogs with Myxomatous Mitral Valve Disease.
Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Clinical applications of blood cell ratios in veterinary hematology: From diagnosis to prognosis.Veterinary and animal science · 2026Review
- Evaluation of Urinary Tubular Biomarkers in Dogs with Myxomatous Mitral Valve Disease Across ACVIM Stages.Veterinary sciences · 2026Article
- Relationship Between Red Blood Cell Indices and Myxomatous Mitral Valve Disease in Small-Breed Dogs: A Retrospective Study.Veterinary medicine and science · 2025Article
- Article
- Neutrophil-to-lymphocyte ratio and red blood cell distribution width to platelet ratio and their relationships with inflammatory and antioxidant status in dogs with different stages of heart failure due to myxomatous mitral valve disease.Veterinary research communications · 2024Article
- Hematological ratios and indices in canine large B-cell lymphoma.Open veterinary journal · 2024Article
- Red Blood Cell Distribution Width as a Novel Parameter in Canine Disorders: Literature Review and Future Prospective.Animals : an open access journal from MDPI · 2023Review
- Comparison of visual assessments of anisocytosis in canine blood smears and analyzer-calculated red blood cell distribution width.Frontiers in veterinary science · 2023Article
- Investigation of red blood cell and platelet indices in adult dogs suffered from myxomatous mitral valve disease with and without pulmonary hypertension.Frontiers in veterinary science · 2023Article
- Prognostic Role of Red Cell Distribution Width and Other Routine Clinico-Pathological Parameters in Dogs with Acute Pancreatitis.Animals : an open access journal from MDPI · 2022Article
- Red blood cell distribution width to platelet ratio in neonatal foals with sepsis.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Red cell distribution width (RDW) is a quantitative measurement of anisocytosis. This hematological parameter is an important prognostic biomarker for different cardiovascular disorders in humans but its influence on survival has been poorly investigated in dogs with cardiovascular disease. The RDW and various clinical, complete blood count, serum biochemical and echocardiographic variables were retrospectively investigated in 146 client-owned dogs with myxomatous mitral valve disease (MMVD) at various disease stages, with or without concurrent diseases and treatment. Laboratory variables, including RDW, urea, and white blood cell (WBC), in addition to the echocardiographic variable left atrium to aorta ratio were found to be independent predictors of all-cause mortality at six months in a multivariable Cox proportional hazards regression model. In particular, the hazard ratio of RDW was 1.203 (95% confidence interval = 1.045-1.384;
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