Evidence map›Paper›PMID 33799696›Full record

ArticleMolecules (Basel, Switzerland)2021

In Silico Analysis of P450s and Their Role in Secondary Metabolism in the Bacterial Class

Ntombizethu Nokuphiwa Msomi, Tiara Padayachee, Nomfundo Nzuza, Puleng Rosinah Syed, Justyna Dorota Kryś, Wanping Chen, Dominik Gront, David R Nelson, Khajamohiddin Syed

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Deletion of theFrontiers in microbiology · 2024
    Article
  4. Article
  5. Evolution of Cytochrome P450 Enzymes and Their Redox Partners in Archaea.International journal of molecular sciences · 2023
    Article
  6. Cytochromes P450 involved in bacterial RiPP biosyntheses.Journal of industrial microbiology & biotechnology · 2023
    Review
  7. Article
  8. Lifestyles Shape the Cytochrome P450 Repertoire of the Bacterial PhylumInternational journal of molecular sciences · 2022
    Article
  9. Contrasting Health Effects ofInternational journal of molecular sciences · 2022
    Article
  10. Article
  11. Article
  12. Ancient Bacterial ClassInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Ntombizethu Nokuphiwa MsomiDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.
Tiara PadayacheeDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.ORCID 0000-0001-6667-9982
Nomfundo NzuzaDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.
Puleng Rosinah SyedDepartment of Pharmaceutical Chemistry, College of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.
Justyna Dorota KryśBiological and Chemical Research Center, Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.
Wanping ChenDepartment of Molecular Microbiology and Genetics, University of Göttingen, 37077 Göttingen, Germany.
Dominik GrontBiological and Chemical Research Center, Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.ORCID 0000-0002-2260-2083
David R NelsonDepartment of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Khajamohiddin SyedDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.ORCID 0000-0002-1497-3570
University of Zululand · ZAUniversity of Warsaw · PLUniversity of Göttingen · DEUniversity of KwaZulu-Natal · ZAUniversity of Tennessee Health Science Center · US

Funding

National Research Foundation, South Africa 114159Polish National Science Centre 2018/29/B/ST6/01989
6 · The paper itself

Abstract

The impact of lifestyle on shaping the genome content of an organism is a well-known phenomenon and cytochrome P450 enzymes (CYPs/P450s), heme-thiolate proteins that are ubiquitously present in organisms, are no exception. Recent studies focusing on a few bacterial species such as

Indexed as

BacillotaComputer SimulationCyanobacteriaCytochrome P-450 Enzyme SystemEvolution, MolecularGammaproteobacteriaGenomicsMultigene FamilyMycobacteriumPhylogenySecondary MetabolismStreptomycesCytochrome P-450 Enzyme Systembiosynthetic gene clustersCyanobacteriacytochrome P450 monooxygenasesFirmicutesGammaproteobacteriagenome data mininglifestyleMycobacteriumsecondary metabolismStreptomyces

Identifiers

PMID33799696
PMCPMC7998510
OpenAlexW3133562283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.