Evidence map›Paper›PMID 33799449›Full record

ArticleInternational journal of molecular sciences2021

Hydrolysis of Extracellular ATP by Vascular Smooth Muscle Cells Transdifferentiated into Chondrocytes Generates P

Rene Buchet, Camille Tribes, Valentine Rouaix, Bastien Doumèche, Michele Fiore, Yuqing Wu, David Magne, Saida Mebarek

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Bioinspired Collagen/κ-Carrageenan 3D Matrix forACS biomaterials science & engineering · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. The Potential Role of Connexins in the Pathogenesis of Atherosclerosis.International journal of molecular sciences · 2023
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Rene BuchetInstitute for Molecular and Supramolecular Chemistry and Biochemistry, Université Lyon 1, French National Centre for Scientific Research, F-69622 Lyon, France.ORCID 0000-0002-7966-3856
Camille TribesInstitute for Molecular and Supramolecular Chemistry and Biochemistry, Université Lyon 1, French National Centre for Scientific Research, F-69622 Lyon, France.
Valentine RouaixInstitute for Molecular and Supramolecular Chemistry and Biochemistry, Université Lyon 1, French National Centre for Scientific Research, F-69622 Lyon, France.
Bastien DoumècheInstitute for Molecular and Supramolecular Chemistry and Biochemistry, Université Lyon 1, French National Centre for Scientific Research, F-69622 Lyon, France.ORCID 0000-0003-3458-1029
Michele FioreInstitute for Molecular and Supramolecular Chemistry and Biochemistry, Université Lyon 1, French National Centre for Scientific Research, F-69622 Lyon, France.ORCID 0000-0001-8176-9249
Yuqing WuState Key Laboratory of Supramolecular Structure and Materials, Institute of Theoretical Chemistry, Jilin University, Changchun 130012, China.
David MagneInstitute for Molecular and Supramolecular Chemistry and Biochemistry, Université Lyon 1, French National Centre for Scientific Research, F-69622 Lyon, France.
Saida MebarekInstitute for Molecular and Supramolecular Chemistry and Biochemistry, Université Lyon 1, French National Centre for Scientific Research, F-69622 Lyon, France.
Université Claude Bernard Lyon 1 · FRJilin University · CN

Funding

Partenariat Hubert Curien Campus France PHC Cai Yuanpei Project N° 32065TD
6 · The paper itself

Abstract

(1) Background: Tissue non-specific alkaline phosphatase (TNAP) is suspected to induce atherosclerosis plaque calcification. TNAP, during physiological mineralization, hydrolyzes the mineralization inhibitor inorganic pyrophosphate (PP

Indexed as

Adenosine TriphosphateAlkaline PhosphataseAnimalsAortaAscorbic AcidAtherosclerosisCell TransdifferentiationChondrocytesDiphosphatesGlycerophosphatesHumansMagnetic Resonance SpectroscopyMiceMuscle, Smooth, VascularMyocytes, Smooth MusclePhosphatesAdenosine TriphosphateAlkaline PhosphataseALPL protein, humanAscorbic Acidbeta-glycerophosphoric acidDiphosphatesdiphosphoric acidGlycerophosphatesPhosphatesalkaline phosphataseaortic smooth muscle cellATPcalcificationchondrocytekineticsMOVASnucleotideplaque calcificationpyrophosphate

Identifiers

PMID33799449
PMCPMC8000465
OpenAlexW3138198661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.