Evidence map›Paper›PMID 33799415›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Optical Platform to Analyze a Model Drug-Loading and Releasing Profile Based on Nanoporous Anodic Alumina Gradient Index Filters.

Pankaj Kapruwan, Laura K Acosta, Josep Ferré-Borrull, Lluis F Marsal

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pankaj KapruwanDepartament d'Enginyeria Electrònica, Elèctrica i Automàtica, Universitat Rovira i Virgili, Avinguda Països Catalans 26, 43007 Tarragona, Spain.
Laura K AcostaDepartament d'Enginyeria Electrònica, Elèctrica i Automàtica, Universitat Rovira i Virgili, Avinguda Països Catalans 26, 43007 Tarragona, Spain.
Josep Ferré-BorrullDepartament d'Enginyeria Electrònica, Elèctrica i Automàtica, Universitat Rovira i Virgili, Avinguda Països Catalans 26, 43007 Tarragona, Spain.ORCID 0000-0002-5210-5133
Lluis F MarsalDepartament d'Enginyeria Electrònica, Elèctrica i Automàtica, Universitat Rovira i Virgili, Avinguda Països Catalans 26, 43007 Tarragona, Spain.ORCID 0000-0002-5976-1408
Universitat Rovira i Virgili · ES

Funding

Agència de Gestió d'Ajuts Universitaris i de Recerca 2017-SGR- 1527Institució Catalana de Recerca i Estudis Avançats ICREA AcademiaMinisterio de Ciencia, Innovación y Universidades RTI2018-094040-B-I00
6 · The paper itself

Abstract

In this work, a methodology that exploits the optical properties of the nanoporous anodic alumina gradient index filters (NAA-GIFs) has been developed and applied to evaluate in real time the release dynamics of a cargo molecule, acting as a model drug, filling the pores. NAA-GIFs with two photonic stopbands (PSBs) were prepared with one of its stop bands in the same absorption wavelength range of the cargo molecule, whereas the second stopband away from this absorption range. Numerical simulation and experiments confirm that the relative height of the high reflectance bands in the reflectance spectra of NAA-GIFs filled with the drug can be related to the relative amount of drug filling the pores. This property has been applied in a flow cell setup to measure in real-time the release dynamics of NAA-GIFs with the inner pore surface modified by layer-by-layer deposition of polyelectrolytes and loaded with the cargo molecule. The methodology developed in this work acts as a tool for the study of drug delivery from porous nanostructures.

Indexed as

nanoporous anodic aluminaoptical monitoringphotonic crystalspolyelectrolytesRhodamine 6G

Identifiers

PMID33799415
PMCPMC7998892
OpenAlexW3136430687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.