Evidence map›Paper›PMID 33799331›Full record

ArticleInternational journal of molecular sciences2021

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Marisa Pereira, Diana R Ribeiro, Miguel M Pinheiro, Margarida Ferreira, Stefanie Kellner, Ana R Soares

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
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  7. Review
  8. Unlocking the role of tRNA-derived fragments in shaping breast cancer signaling.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
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  10. Article
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  14. Article
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  16. A Novel tsRNA, mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Marisa PereiraInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810 Aveiro, Portugal.ORCID 0000-0002-8493-0656
Diana R RibeiroInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810 Aveiro, Portugal.
Miguel M PinheiroInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810 Aveiro, Portugal.
Margarida FerreiraInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810 Aveiro, Portugal.
Stefanie KellnerDepartment of Chemistry, Ludwig Maximilians University Munich, 81377 Munich, Germany.
Ana R SoaresInstitute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810 Aveiro, Portugal.ORCID 0000-0003-4000-7461
University of Aveiro · PTGoethe University Frankfurt · DE

Funding

Deutsche Forschungsgemeinschaft KE1943/3-1Fundação para a Ciência e a Tecnologia CEECIND/00284/2018Fundação para a Ciência e a Tecnologia POCI-01-0145-FEDER-016630Fundação para a Ciência e a Tecnologia POCI-01-0145-FEDER-029843Fundação para a Ciência e a Tecnologia SFRH/BD/135655/2018Fundação para a Ciência e a Tecnologia SFRH/BD/146703/2019Fundação para a Ciência e a Tecnologia UIDB/04501/2020Fundação para a Ciência e a Tecnologia UID/ BIM/04501/2013Horizon 2020 H2020-WIDESPREAD-2020-5 ID-952373Programa Operacional Regional do Centro pAGE-Centro-01-0145-FEDER-000003
6 · The paper itself

Abstract

Transfer RNA (tRNA) molecules contain various post-transcriptional modifications that are crucial for tRNA stability, translation efficiency, and fidelity. Besides their canonical roles in translation, tRNAs also originate tRNA-derived small RNAs (tsRNAs), a class of small non-coding RNAs with regulatory functions ranging from translation regulation to gene expression control and cellular stress response. Recent evidence indicates that tsRNAs are also modified, however, the impact of tRNA epitranscriptome deregulation on tsRNAs generation is only now beginning to be uncovered. The 5-methyluridine (m

Indexed as

HumansOxidative StressRibonuclease, PancreaticRNA CleavageRNA Processing, Post-TranscriptionalRNA, Small UntranslatedRNA StabilityRNA, TransferStress, PhysiologicaltRNA MethyltransferasesUridineangiogeninRibonuclease, PancreaticribothymidineRNA, Small UntranslatedRNA, TransfertRNA MethyltransferasesUridineangiogeninmethyltransferaseTRMT2AtRNA-derived small RNAstRNA-derived stress-induced RNAstRNA hypomethylationtRNA-modifying enzymetRNAs

Identifiers

PMID33799331
PMCPMC8001983
OpenAlexW3136534007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.