Evidence map›Paper›PMID 33798931›Full record

ArticleEuropean journal of radiology2021

Post-discharge chest CT findings and pulmonary function tests in severe COVID-19 patients.

Maurizio Balbi, Caterina Conti, Gianluca Imeri, Anna Caroli, Alessandra Surace, Andrea Corsi, Elisa Mercanzin, Alberto Arrigoni, Giulia Villa, Fabiano Di Marco and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in European journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 103 citations in OpenAlex.

  1. Post-COVID-19 dyspnoea and pulmonary imaging: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
  2. ESCMID rapid guidelines for assessment and management of long COVID.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Maurizio BalbiDepartment of Radiology, ASST Papa Giovanni XXIII, Piazza OMS 1, Bergamo, BG, 24127, Italy; Post Graduate School of Diagnostic Radiology, University of Milan-Bicocca, Piazza dell'Ateneo Nuovo 1, Milano, MI, 20126, Italy. Electronic address: balbi.m@libero.it.
Caterina ContiRespiratory Unit, ASST Papa Giovanni XXIII, Piazza OMS 1, Bergamo, BG, 24127, Italy.
Gianluca ImeriRespiratory Unit, ASST Papa Giovanni XXIII, Piazza OMS 1, Bergamo, BG, 24127, Italy.
Anna CaroliBioengineering Department, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Gian Battista Camozzi 3, Ranica, BG, 24020, Italy.
Alessandra SuraceDepartment of Radiology, ASST Papa Giovanni XXIII, Piazza OMS 1, Bergamo, BG, 24127, Italy; Post Graduate School of Diagnostic Radiology, University of Milan-Bicocca, Piazza dell'Ateneo Nuovo 1, Milano, MI, 20126, Italy.
Andrea CorsiDepartment of Radiology, ASST Papa Giovanni XXIII, Piazza OMS 1, Bergamo, BG, 24127, Italy; Post Graduate School of Diagnostic Radiology, University of Milan-Bicocca, Piazza dell'Ateneo Nuovo 1, Milano, MI, 20126, Italy.
Elisa MercanzinDepartment of Radiology, ASST Papa Giovanni XXIII, Piazza OMS 1, Bergamo, BG, 24127, Italy; Post Graduate School of Diagnostic Radiology, University of Milan-Bicocca, Piazza dell'Ateneo Nuovo 1, Milano, MI, 20126, Italy.
Alberto ArrigoniDepartment of Management, Information and Production Engineering, University of Bergamo, Via Pasubio 3, Dalmine, BG, 24044, Italy.
Giulia VillaBioengineering Department, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Gian Battista Camozzi 3, Ranica, BG, 24020, Italy.
Fabiano Di MarcoRespiratory Unit, ASST Papa Giovanni XXIII, Piazza OMS 1, Bergamo, BG, 24127, Italy; Department of Health Sciences, University of Milan, Via di Rudinì 8, Milano, MI, 20146, Italy.
Pietro Andrea BonaffiniDepartment of Radiology, ASST Papa Giovanni XXIII, Piazza OMS 1, Bergamo, BG, 24127, Italy; Post Graduate School of Diagnostic Radiology, University of Milan-Bicocca, Piazza dell'Ateneo Nuovo 1, Milano, MI, 20126, Italy.
Sandro SironiDepartment of Radiology, ASST Papa Giovanni XXIII, Piazza OMS 1, Bergamo, BG, 24127, Italy; Post Graduate School of Diagnostic Radiology, University of Milan-Bicocca, Piazza dell'Ateneo Nuovo 1, Milano, MI, 20126, Italy.
Ospedale Papa Giovanni XXIII · ITMario Negri Institute for Pharmacological Research · ITUniversity of Bergamo · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate chest computed tomography (CT) and pulmonary function test (PFT) findings in severe COVID-19 patients after discharge and correlate CT pulmonary involvement with PFT results.

methodsCOVID-19 patients admitted to our hospital between February 25 and May 2, 2020, were retrospectively included according to the following criteria: (a) COVID-19 defined as severe based on the WHO interim guidance (i.e., clinical signs of pneumonia plus respiratory rate > 30 breaths/min, severe respiratory distress, and/or SpO

resultsAt a median of 105 days from symptom onset, 74/91 (81 %) patients had CT abnormalities. The most common CT pattern was combined ground-glass opacity and reticular pattern (46/74, 62 %) along with architectural distortion (68/74, 92 %) and bronchial dilatation (66/74, 89 %). Compromised lung volume had a median value of 15 % [11-23], was higher in dyspneic patients, and negatively correlated with the percentage of predicted DLCO, VA, and FVC values (r = -0.39, -0.5, and -0.42, respectively). These PFT parameters were significantly lower in patients with CT abnormalities. Impairment of DLCO and KCO was found in 12 (13 %) cases, possibly implying an underlying pulmonary vasculopathy in this subgroup of patients.

conclusionsMost severe COVID-19 survivors still had physiologically relevant CT abnormalities about three months after the disease onset, with an impairment of diffusion capacity on PFT. A pulmonary vasculopathy was suggested in a minor proportion of patients.

Indexed as

COVID-19AftercareHumansLungPatient DischargeRespiratory Function TestsRetrospective StudiesSARS-CoV-2Tomography, X-Ray ComputedCOVID-19Lung diseasesRespiratory function testsSevere acute respiratory syndrome coronavirus 2SurvivorsTomography

Identifiers

PMID33798931
PMCPMC7980523
OpenAlexW3137119208

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.