Evidence map›Paper›PMID 33798918›Full record

ArticleAddictive behaviors2021

Youth use of e-cigarettes: Does dependence vary by device type?

Alayna P Tackett, Emily T Hébert, Caitlin E Smith, Samantha W Wallace, Jessica L Barrington-Trimis, Jordan E Norris, William V Lechner, Elise M Stevens, Theodore L Wagener

Registry-linked trialAbstract read
In one paragraph

Article in Addictive behaviors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06506162 (The Effect of Flavor and Nicotine Strength on the Abuse Liability and Appeal of Oral Nicotine Products), which is not on this map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06506162 narecruitingnot on this mapstarted 2024, after this paper: background citation

The Effect of Flavor and Nicotine Strength on the Abuse Liability and Appeal of Oral Nicotine Products

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2024 to 2028Enrolled320ConditionsNicotine DependenceArmsFlavor, Nicotine concentration
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. What is the Addictive Potential from Vaping?Nordisk alkohol- & narkotikatidskrift : NAT · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Preventive medicine reports · 2025
    Article
  9. Observational
  10. Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alayna P TackettDepartment of Preventive Medicine, Keck School of Medicine of USC, University of Southern California, USA. Electronic address: Alayna.Tackett@usc.edu.
Emily T HébertSchool of Public Health Austin, University of Texas Health Sciences Center, USA.
Caitlin E SmithDepartment of Psychology, Oklahoma State University, USA.
Samantha W WallaceUniversity of North Texas Health Science Center, USA.
Jessica L Barrington-TrimisDepartment of Preventive Medicine, Keck School of Medicine of USC, University of Southern California, USA.
Jordan E NorrisDepartment of Psychology, University of Oklahoma, USA.
William V LechnerDepartment of Psychology, Kent State University, USA.
Elise M StevensDivision of Preventive of Behavioral Medicine, Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, USA.
Theodore L WagenerDivision of Medical Oncology, Department of Internal Medicine, Ohio State University Wexner Medical Center, USA; Center for Tobacco Research, Ohio State University Comprehensive Cancer Center, USA.

Funding

Examination of First and Second Generation E-cigarettesR01CA204891 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI WAGENER, THEODORE LEE · 2016 to 2020
$3.0M
Respiratory effects of E-Cigarette use among Youth: A prospective, longitudinal investigationK01HL148907 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TACKETT, ALAYNA PAULINE · 2019 to 2023
$981k
Young Adults Responses to E-Cigarette Advertisement Features and the Effects of Restricting Features on Tobacco UseR00DA046563 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STEVENS, ELISE MARIE · 2021 to 2023
$914k
Using Machine Learning to Develop Just-in-Time Adaptive Interventions for Smoking CessationR00DA046564 · NIDA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HEBERT, EMILY TAYLOR · 2021 to 2023
$747k
Young Adults Responses to E-Cigarette Advertisement Features and the Effect of Restricting Features on Tobacco UseK99DA046563 · NIDA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI STEVENS, ELISE MARIE · 2019 to 2020
$237k
NCI NIH HHS R01 CA204891NHLBI NIH HHS K01 HL148907NIDA NIH HHS K99 DA046563NIDA NIH HHS R00 DA046563NIDA NIH HHS R00 DA046564
6 · The paper itself

Abstract

introductionYouth nicotine dependence may vary by e-cigarette device used.

methodsE-cigarette device type ("JUUL," "similar pod/JUUL like device (i.e., pod mod)," or "other type of e-cigarette" (i.e., tank, mod)), nicotine dependence (Hooked on Nicotine Checklist; HONC), frequency of e-cigarette use (i.e., weekly, daily, monthly), and covariates were examined via a convenience sample of youth who use e-cigarettes in the United States via an online Qualtrics panel survey from April 2019 to May 2019.

resultsYouth aged 13-17 (Mean age = 15.9 years, SD = 1.0 year; n = 185) were mostly 72.4% female. Primary device used by category was endorsed as follows: JUUL n = 87, pod mod n = 42, and other type of e-cigarette n = 56. Participants endorsed an average of 4.5 / 10 HONC symptoms (SD = 3.6). Compared to other e-cigarettes, youth who used JUUL and pod mod devices endorsed more dependence symptoms, even when adjusting for current smoking status (JUUL IRR = 1.96, 95% CI 1.30-2.97; pod mod device IRR = 1.76, 95% CI 1.08-2.87). In total, HONC symptoms significantly differed by device for 8/10 symptoms, with JUUL and pod mod users reporting higher frequency of items compared to other e-cigarette devices.

conclusionsFeatures of nicotine dependence experienced by youth (i.e., feeling a stronger urge to vape) differed by primary device used, with those using JUUL and pod-mods reporting a greater level of dependence. Regulation of features of e-cigarette devices that may increase nicotine delivery and subsequent development of dependence among youth warrant urgent consideration.

Indexed as

Electronic Nicotine Delivery SystemsTobacco Use DisorderVapingAdolescentFemaleHumansMaleSurveys and QuestionnairesUnited StatesE-cigarettesNicotine dependenceYouth

Identifiers

PMID33798918
PMCPMC8113136

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.