Evidence map›Paper›PMID 33798915›Full record

ArticleComputerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society2021

Rapid analysis of streaming platelet images by semi-unsupervised learning.

Ziji Zhang, Peng Zhang, Peineng Wang, Jawaad Sheriff, Danny Bluestein, Yuefan Deng

Abstract read
In one paragraph

Article in Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Modeling of the thermal properties of SARS-CoV-2 S-protein.Frontiers in molecular biosciences · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ziji ZhangDepartment of Applied Mathematics and Statistics, Stony Brook University, NY, 11794, United States. Electronic address: ziji.zhang@stonybrook.edu.
Peng ZhangDepartment of Applied Mathematics and Statistics, Stony Brook University, NY, 11794, United States; Department of Biomedical Engineering, Stony Brook University, NY, 11794, United States. Electronic address: peng.zhang@stonybrook.edu.
Peineng WangDepartment of Biomedical Engineering, Stony Brook University, NY, 11794, United States. Electronic address: peineng.wang@stonybrook.edu.
Jawaad SheriffDepartment of Biomedical Engineering, Stony Brook University, NY, 11794, United States. Electronic address: jawaad.sheriff@stonybrook.edu.
Danny BluesteinDepartment of Biomedical Engineering, Stony Brook University, NY, 11794, United States. Electronic address: danny.bluestein@stonybrook.edu.
Yuefan DengDepartment of Applied Mathematics and Statistics, Stony Brook University, NY, 11794, United States. Electronic address: yuefan.deng@stonybrook.edu.

Funding

Multiscale Modeling of Blood Flow and Platelet Mediated ThrombosisU01HL131052 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI BLUESTEIN, DANNY · 2016 to 2020
$3.6M
NHLBI NIH HHS U01 HL131052
6 · The paper itself

Abstract

We developed a fast and accurate deep learning approach employing a semi-unsupervised learning system (SULS) for capturing the real-time noisy, sparse, and ambiguous images of platelet activation. Outperforming several leading supervised learning methods when applied to segment various platelet morphologies, the SULS detects their complex boundaries at submicron resolutions and it massively decreases to only a few hours for segmenting streaming images of 45 million platelets that would have taken 40 years to annotate manually. For the first time, the fast dynamics of pseudopod formation and platelet morphological changes including membrane tethers and transient tethering to vessels are accurately captured.

Indexed as

Image Processing, Computer-AssistedUnsupervised Machine LearningBlood PlateletsDeep learningMedical imagingPlateletsSegmentation

Identifiers

PMID33798915
PMCPMC8612242

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.