Evidence map›Paper›PMID 33798655›Full record

ArticleOphthalmology2021

The Effect of Transitioning from SITA Standard to SITA Faster on Visual Field Performance.

Alex T Pham, Pradeep Y Ramulu, Michael V Boland, Jithin Yohannan

Open access · greenAbstract read
In one paragraph

Article in Ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Clinical Effective Dynamic Range and the Measurement Floor of SITA-Faster Visual Field Tests.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
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  18. Big data in visual field testing for glaucoma.Taiwan journal of ophthalmology
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alex T PhamWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Pradeep Y RamuluWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Michael V BolandMassachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.
Jithin YohannanWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: jithin@jhmi.edu.
Johns Hopkins Medicine · USHarvard University · US

Funding

Wilmer Inst. Mentored Clinical Research Scholar ProgramK12EY015025 · NEI · JOHNS HOPKINS UNIVERSITY · PI James T Handa, Harry Alan Quigley · 2003 to 2026
$8.6M
A Comprehensive Strategy to Detect Glaucoma Worsening Earlier and With Fewer TestsK23EY032204 · NEI · JOHNS HOPKINS UNIVERSITY · PI YOHANNAN, JITHIN · 2021 to 2025
$956k
NEI NIH HHS K12 EY015025NEI NIH HHS K23 EY032204
6 · The paper itself

Abstract

purposeTo determine the effect of transitioning from Swedish Interactive Thresholding Algorithm (SITA) Standard to SITA Faster on visual field (VF) performance in glaucomatous eyes with a broad spectrum of disease severity undergoing longitudinal VF testing in a real-world clinical setting.

designRetrospective, longitudinal study.

participantsA total of 421 patients (766 eyes) with manifest or suspect glaucoma followed at a single institution.

methodsEach included eye received the following sequence of VF examinations during routine clinical care: (1) SITA Standard, (2) SITA Standard, and (3) SITA Faster (mean time between tests = 13.9 months). Intra-eye comparisons were made between the first 2 VFs (Standard-Standard sequence) and the last 2 VFs (Standard-Faster sequence). The primary dependent variable was the difference in mean deviation (MD) between the second and first VF of the sequence (ΔMD, calculated as MD

main outcome measuresThe difference in ΔMD between Standard-Standard and Standard-Faster sequence by mild, moderate, and advanced disease severity.

resultsIn eyes with mild or suspect glaucoma, there was no significant difference in ΔMD between Standard-Faster and Standard-Standard sequences (-0.23 decibels [dB]; 95% confidence interval [CI], -0.60 to 0.15 dB). However, the Standard-Faster sequence was associated with a 0.87 dB (95% CI, 0.18-1.57 dB) improvement in ΔMD compared with the Standard-Standard sequence in eyes with moderate glaucoma and a 1.49 dB (95% CI, 0.79-2.19 dB) improvement in ΔMD in eyes with advanced glaucoma.

conclusionsConverting to SITA Faster in eyes that were previously followed with SITA Standard led to similar VF performance in mild glaucoma but resulted in higher MD values in moderate and advanced glaucoma. For patients with moderate or severe glaucoma, this may conceal disease progression when transitioning testing strategies.

Indexed as

AgedAlgorithmsDisease ProgressionFemaleFollow-Up StudiesGlaucomaHumansIntraocular PressureMaleOcular HypertensionRetrospective StudiesSeverity of Illness IndexSwedenVisual FieldsVisual Field TestsMean deviationSITA FasterSITA StandardVisual field

Identifiers

PMID33798655
PMCPMC8463413
OpenAlexW3148127584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.