Evidence map›Paper›PMID 33798452›Full record

ArticleStem cell reports2021

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.

Pauline Antonie Ulmke, M Sadman Sakib, Peter Ditte, Godwin Sokpor, Cemil Kerimoglu, Linh Pham, Yuanbin Xie, Xiaoyi Mao, Joachim Rosenbusch, Ulrike Teichmann and 5 more

Open access · goldAbstract read
In one paragraph

Article in Stem cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Pauline Antonie UlmkeInstitute for Neuroanatomy, University Medical Center, Georg-August-University, Goettingen, Germany.
M Sadman SakibGerman Center for Neurodegenerative Diseases, Goettingen, Germany.
Peter DitteMax-Planck-Institute for Biophysical Chemistry, Goettingen, Germany.
Godwin SokporInstitute for Neuroanatomy, University Medical Center, Georg-August-University, Goettingen, Germany; Department of Human Genetics, Ruhr University of Bochum, Bochum, Germany.
Cemil KerimogluGerman Center for Neurodegenerative Diseases, Goettingen, Germany.
Linh PhamInstitute for Neuroanatomy, University Medical Center, Georg-August-University, Goettingen, Germany; Department of Human Genetics, Ruhr University of Bochum, Bochum, Germany.
Yuanbin XieInstitute for Neuroanatomy, University Medical Center, Georg-August-University, Goettingen, Germany.
Xiaoyi MaoInstitute for Neuroanatomy, University Medical Center, Georg-August-University, Goettingen, Germany.
Joachim RosenbuschInstitute for Neuroanatomy, University Medical Center, Georg-August-University, Goettingen, Germany.
Ulrike TeichmannMax-Planck-Institute for Biophysical Chemistry, Goettingen, Germany.
Huu Phuc NguyenDepartment of Human Genetics, Ruhr University of Bochum, Bochum, Germany.
Andre FischerGerman Center for Neurodegenerative Diseases, Goettingen, Germany; Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), Goettingen, Germany.
Gregor EicheleMax-Planck-Institute for Biophysical Chemistry, Goettingen, Germany.
Jochen F StaigerInstitute for Neuroanatomy, University Medical Center, Georg-August-University, Goettingen, Germany.
Tran TuocInstitute for Neuroanatomy, University Medical Center, Georg-August-University, Goettingen, Germany; Department of Human Genetics, Ruhr University of Bochum, Bochum, Germany. Electronic address: tran.tuoc@ruhr-uni-bochum.de.
University of Göttingen · DERuhr University Bochum · DEGerman Center for Neurodegenerative Diseases · DEMax Planck Institute for Biophysical Chemistry · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intermediate progenitor cells (IPCs) are neocortical neuronal precursors. Although IPCs play crucial roles in corticogenesis, their molecular features remain largely unknown. In this study, we aimed to characterize the molecular profile of IPCs. We isolated TBR2-positive (+) IPCs and TBR2-negative (-) cell populations in the developing mouse cortex. Comparative genome-wide gene expression analysis of TBR2

Indexed as

Gene Expression ProfilingAcetyltransferasesAnimalsApoptosisCerebral CortexChromatidsChromosome SegregationGene Expression RegulationHumansMiceMitosisMutationNeural Stem CellsNeurodevelopmental DisordersSignal TransductionAcetyltransferasesestablishment of cohesion 1 homolog 2, mouseapoptosiscell-cycle regulationchromosome segregationcortical developmentcortical malformationESCO2intermediate progenitor cellssignaling pathwaysTBR2transcription factorstranscriptome

Identifiers

PMID33798452
PMCPMC8072132
OpenAlexW3140921547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.