Evidence map›Paper›PMID 33798090›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2021

Medication-related harm in New Zealand general practice: a retrospective records review.

Sharon Leitch, Susan M Dovey, Wayne K Cunningham, Alesha J Smith, Jiaxu Zeng, David M Reith, Katharine A Wallis, Kyle S Eggleton, Andrew W McMenamin, Martyn I Williamson and 1 more

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Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Treatment Harms in Paediatric Primary Care.International journal of environmental research and public health · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sharon LeitchDepartment of General Practice and Rural Health, Otago Medical School, Dunedin Campus, University of Otago, Dunedin, New Zealand.
Susan M DoveyDepartment of General Practice and Rural Health, Otago Medical School, Dunedin Campus, University of Otago, Dunedin, New Zealand.
Wayne K CunninghamDepartment of Family Medicine, Royal College of Surgeons in Ireland, Medical University of Bahrain (RCSI Bahrain), Adliya, Bahrain.
Alesha J SmithSchool of Pharmacy, University of Otago, Dunedin, New Zealand.
Jiaxu ZengDepartment of Preventive and Social Medicine, Otago Medical School, Dunedin Campus, University of Otago, Dunedin, New Zealand.
David M ReithOtago Medical School, Dunedin Campus, University of Otago, Dunedin, New Zealand.
Katharine A WallisUniversity of Queensland, Brisbane, Australia.
Kyle S EggletonFaculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Andrew W McMenaminTe Ngae Medical Centre, Rotorua, New Zealand.
Martyn I WilliamsonDepartment of General Practice and Rural Health, Otago Medical School, Dunedin Campus, University of Otago, Dunedin, New Zealand.
Steven LillisFaculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe extent of medication-related harm in general practice is unknown.

aimTo identify and describe all medication-related harm in electronic general practice records. The secondary aim was to investigate factors potentially associated with medication-related harm. DESIGN AND

settingRetrospective cohort records review study in 44 randomly selected New Zealand general practices for the 3 years 2011-2013.

methodEight GPs reviewed 9076 randomly selected patient records. Medication-related harms were identified when the causal agent was prescribed in general practice. Harms were coded by type, preventability, and severity. The number and proportion of patients who experienced medication-related harm was calculated. Weighted logistic regression was used to identify factors associated with harm.

resultsIn total, 976 of 9076 patients (10.8%) experienced 1762 medication-related harms over 3 years. After weighting, the incidence rate of all medication-related harms was 73.9 harms per 1000 patient-years, and the incidence of preventable, or potentially preventable, medication-related harms was 15.6 per 1000 patient-years. Most harms were minor (

conclusionMedication-related harm in general practice is common. This study adds to the evidence about the risk posed by medication in the real world. Findings can be used to inform decision making in general practice.

Indexed as

General PracticeFamily PracticeHospitalizationHumansNew ZealandRetrospective Studiesgeneral practiceNew Zealandpatient harmprimary health careretrospective studies

Identifiers

PMID33798090
PMCPMC8252858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.