Evidence map›Paper›PMID 33797937›Full record

ArticleEnvironmental health perspectives2021

Associations of Pre- and Postnatal Air Pollution Exposures with Child Blood Pressure and Modification by Maternal Nutrition: A Prospective Study in the CANDLE Cohort.

Yu Ni, Adam A Szpiro, Michael T Young, Christine T Loftus, Nicole R Bush, Kaja Z LeWinn, Sheela Sathyanarayana, Daniel A Enquobahrie, Robert L Davis, Mario Kratz and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Review
  3. Gestational diabetes and childhood lung function at age 8 to 9 years in a diverse US cohort.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026
    Article
  4. Pre- and postnatal exposure to PMEnvironmental research · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Associations Between Prenatal Vitamin D and Placental Gene Expression.bioRxiv : the preprint server for biology · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Yu NiDepartment of Epidemiology, School of Public Health, University of Washington (UW), Seattle, Washington, USA.
Adam A SzpiroDepartment of Biostatistics, School of Public Health, UW, Seattle, Washington, USA.
Michael T YoungDepartment of Environmental and Occupational Health Sciences, School of Public Health, UW, Seattle, Washington, USA.
Christine T LoftusDepartment of Environmental and Occupational Health Sciences, School of Public Health, UW, Seattle, Washington, USA.
Nicole R BushDepartment of Psychiatry, School of Medicine, University of California, San Francisco (UCSF), San Francisco, California, USA.
Kaja Z LeWinnDepartment of Psychiatry, School of Medicine, University of California, San Francisco (UCSF), San Francisco, California, USA.
Sheela SathyanarayanaDepartment of Environmental and Occupational Health Sciences, School of Public Health, UW, Seattle, Washington, USA.
Daniel A EnquobahrieDepartment of Epidemiology, School of Public Health, University of Washington (UW), Seattle, Washington, USA.
Robert L DavisCenter for Biomedical Informatics, University of Tennessee Health Science Center (UTHSC), Memphis, Tennessee, USA.
Mario KratzDepartment of Epidemiology, School of Public Health, University of Washington (UW), Seattle, Washington, USA.
Annette L FitzpatrickDepartment of Epidemiology, School of Public Health, University of Washington (UW), Seattle, Washington, USA.
Jennifer T SonneyDepartment of Child, Family, and Population Health Nursing, School of Nursing, UW, Seattle, Washington, USA.
Frances A TylavskyDepartment of Preventive Medicine, UTHSC, Memphis, Tennessee, USA.
Catherine J KarrDepartment of Epidemiology, School of Public Health, University of Washington (UW), Seattle, Washington, USA.
University of Washington · USUniversity of California, San Francisco · USUniversity of Tennessee Health Science Center · USCancer Research And Biostatistics · US

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUH3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2018 to 2022
$37.3M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUG3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2016 to 2017
$5.1M
Pregnancy Folate Status & Early Childhood Respiratory & Atopic Disease OutcomesR01HL109977 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CARROLL, KECIA NICOLE · 2011 to 2015
$3.4M
NHLBI NIH HHS R01 HL109977NIEHS NIH HHS P30 ES007033NIH HHS UG3 OD023271NIH HHS UH3 OD023271
6 · The paper itself

Abstract

backgroundLimited data suggest air pollution exposures may contribute to pediatric high blood pressure (HBP), a known predictor of adult cardiovascular diseases.

methodsWe investigated this association in the Conditions Affecting Neurocognitive Development and Learning in Early Childhood (CANDLE) study, a sociodemographically diverse pregnancy cohort in the southern United States with participants enrolled from 2006 to 2011. We included 822 mother-child dyads with available address histories and a valid child blood pressure measurement at 4-6 y. Systolic (SBP) and diastolic blood pressures (DBP) were converted to age-, sex-, and height-specific percentiles for normal-weight U.S. children. HBP was classified based on SBP or DBP

resultsMean

conclusionsThe findings suggest that higher prenatal

Indexed as

Air PollutantsAir PollutionAdultBlood PressureChildChild, PreschoolEnvironmental ExposureFemaleHumansParticulate MatterPregnancyProspective StudiesAir PollutantsParticulate Matter

Identifiers

PMID33797937
PMCPMC8043131
OpenAlexW3148335435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.