Evidence map›Paper›PMID 33797935›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2021

Inhibition of KIT Tyrosine Kinase Activity: Two Decades After the First Approval.

Lillian R Klug, Christopher L Corless, Michael C Heinrich

Abstract read
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lillian R KlugOregon Health & Science University, Knight Cancer Institute, Portland, OR.
Christopher L CorlessOregon Health & Science University, Knight Cancer Institute, Portland, OR.
Michael C HeinrichOregon Health & Science University, Knight Cancer Institute, Portland, OR.ORCID 0000-0003-3790-0478

Funding

Novel models for functional profiling of germline SDH variants associated with cancerR21CA263400 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HEINRICH, MICHAEL C · 2021 to 2022
$320k
Regulation of oncogenic KIT by LMTK3I01BX000338 · VA · PORTLAND VA MEDICAL CENTER · PI HEINRICH, MICHAEL C · 2009 to 2019
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Functional profiling of germline SDH variants associated with cancer susceptibilityI01BX005358 · VA · PORTLAND VA MEDICAL CENTER · PI HEINRICH, MICHAEL C · 2021 to 2025
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BLRD VA I01 BX000338BLRD VA I01 BX005358NCI NIH HHS R21 CA263400
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansProtein-Tyrosine KinasesProto-Oncogene Proteins c-kitKIT protein, humanProtein-Tyrosine KinasesProto-Oncogene Proteins c-kit

Identifiers

PMID33797935
PMCPMC8274803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.