Evidence map›Paper›PMID 33797912›Full record

ArticleJournal of proteome research2021

Iron Deficiency and Recovery in Yeast: A Quantitative Proteomics Approach.

Jose Navarrete-Perea, Angel Guerra-Moreno, Jonathan Van Vranken, Marta Isasa, Joao A Paulo, Steven P Gygi

Open access · greenAbstract read
In one paragraph

Article in Journal of proteome research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Phenomic and Transcriptomic Profiling of ZnS QD Response inNanomaterials (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jose Navarrete-PereaDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts 02155, United States.ORCID 0000-0001-6265-6214
Angel Guerra-MorenoBrigham and Women's Hospital, Boston, Massachusetts 02115, United States.
Jonathan Van VrankenDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts 02155, United States.
Marta IsasaC4 Therapeutics, Cambridge, Massachusetts 02142, United States.
Joao A PauloDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts 02155, United States.
Steven P GygiDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts 02155, United States.ORCID 0000-0001-7626-0034
Harvard University · USBrigham and Women's Hospital · USC4 Therapeutics (United States) · US

Funding

New Sample Multiplexing Technologies to Identify Chemical Probes and Illuminate Ubiquitin BiologyR01GM067945 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GYGI, STEVEN P · 2003 to 2024
$10.5M
Advancing Multiplexed Isobaric Tag-based Strategies for Proteome ProfilingR01GM132129 · NIGMS · HARVARD MEDICAL SCHOOL · PI PAULO, JOAO A · 2019 to 2023
$1.7M
NIGMS NIH HHS R01 GM067945NIGMS NIH HHS R01 GM132129
6 · The paper itself

Abstract

Iron is an essential element for life, as it is critical for oxygen transport, cellular respiration, DNA synthesis, and metabolism. Disruptions in iron metabolism have been associated with several complex diseases like diabetes, cancer, infection susceptibility, neurodegeneration, and others; however, the molecular mechanisms linking iron metabolism with these diseases are not fully understood. A commonly used model to study iron deficiency (ID) is yeast,

Indexed as

Anemia, Iron-DeficiencySaccharomyces cerevisiae ProteinsHumansIronProteomicsSaccharomyces cerevisiaeIronSaccharomyces cerevisiae Proteinsiron−sulfur clusternutritional deficiencyOrbitrap FusionSL-TMTubiquitin-proteasome system

Identifiers

PMID33797912
PMCPMC8210944
OpenAlexW3147483104

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.