Evidence map›Paper›PMID 33797760›Full record

ArticleThe Laryngoscope2021

Applicability of Selective Electrical Surface Stimulation in Unilateral Vocal Fold Paralysis.

Annabella Kurz, Matthias Leonhard, Guan-Yuh Ho, Ines Kansy, Berit Schneider-Stickler

Open access · hybridAbstract read
In one paragraph

Article in The Laryngoscope, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. [Analysis of the efficacy of non-surgical treatment mainly focus on voice therapy and it's influencing factors in patients with unilateral vocal fold paralysis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Annabella KurzDepartment of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-0637-6880
Matthias LeonhardDepartment of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria.
Guan-Yuh HoDepartment of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria.
Ines KansyDepartment of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria.
Berit Schneider-SticklerDepartment of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · AT

Funding

MED-EL Elektromedizinische Geräte GmbH, Innsbruck, Austria
6 · The paper itself

Abstract

objectiveSelective electrical surface stimulation (SES) of the larynx is not yet routinely considered therapy option in treatment of unilateral vocal fold paralysis (UVFP). Goal of this monocentric feasibility study was to provide systematic data on applicability of SES of intrinsic laryngeal muscles in UVFP under consideration of sensitivity and discomfort thresholds and nonselective side effects.

methodsThirty-two UVFP patients were included in the study. Symmetric triangular-shape, charge-balanced pulse widths (PWs) of 1, 10, 25, 50, 100, 250, and 500 milliseconds (ms) were tested with increasing amplitudes (AMPs). The stimulation was delivered as a train of five pulses using square surface electrodes. Selective laryngeal responses were examined by flexible laryngoscopy. Nonselective side effects (swallowing reflex, coughing, different severity degrees of unspecific strap muscle/platysma response) were judged by observation.

resultsSelective laryngeal response could be triggered in 28/32 (87.5%) patients during respiration/rest and in 26/32 (81.3%) patients during phonation. The most effective PWs for the selective eliciting of selective bilateral vocal fold adduction are comprised between 50 and 100 ms in combination with an average AMP comprised between 7.1 and 7.2 mA.

conclusionOur results indicate that, in UVFP patients, PWs comprised between 50 and 100 ms in combination with a median AMP between 7.1 and 7.2 mA are expected to deliver in >75% of the cases a specific, effective, and safe bilateral adduction of the VF. LEVEL OF EVIDENCE: 3 Laryngoscope, 131:E2566-E2572, 2021.

Indexed as

Electric Stimulation TherapyFeasibility StudiesFemaleHumansMaleMiddle AgedPain MeasurementVocal Cord ParalysisatrophyElectrical laryngeal stimulationvocal fold paralysisvoice therapy

Identifiers

PMID33797760
PMCPMC8451789
OpenAlexW3140316926

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.