Evidence map›Paper›PMID 33797727›Full record

ReviewLa Radiologia medica2021

Differentiation between infectious spondylodiscitis versus inflammatory or degenerative spinal changes: How can magnetic resonance imaging help the clinician?

Fausto Salaffi, Luca Ceccarelli, Marina Carotti, Marco Di Carlo, Gabriele Polonara, Giancarlo Facchini, Rita Golfieri, Andrea Giovagnoni

Open access · hybridAbstract readReview
In one paragraph

Review in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. The role of metagenomic next-generation sequencing in spinal infections: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
  3. Andersson-like lesion in diffuse idiopathic skeletal hyperostosis; a rare diagnostic and therapeutic challenge.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Non-Infectious Spinal Diseases Mimicking Infection: A Pictorial Essay.Journal of the Korean Society of Radiology · 2025
    Review
  8. Automated radiosynthesis of [EJNMMI radiopharmacy and chemistry · 2025
    Article
  9. Review
  10. Segmentation-based 3D volumetry and linear regression modeling for assessing the vertebral bone loss in pyogenic vertebral osteomyelitis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  11. [Spondylitis and spondylodiscitis].Radiologie (Heidelberg, Germany) · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Diagnostic imaging confusion in infectious spondylitis.Journal of orthopaedic surgery and research · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fausto SalaffiClinica Reumatologica, Ospedale "Carlo Urbani", Dipartimento Di Scienze Cliniche E Molecolari, Università Politecnica Delle Marche, Via Aldo Moro, 25, 60035, Jesi, Ancona, Italy.ORCID http://orcid.org/0000-0002-3794-6831
Luca CeccarelliUnità di Radiologia, Dipartimento di Medicina Specialistica, Diagnostica E Sperimentale, Ospedale Sant'Orsola, Università Di Bologna, Via Albertoni 15, 40138, Bologna, Italy.ORCID http://orcid.org/0000-0002-0510-0970
Marina CarottiDipartimento di Scienze Radiologiche, Ospedali Riuniti, Università Politecnica Delle Marche, Ancona, Italia.ORCID http://orcid.org/0000-0001-6562-180X
Marco Di CarloClinica Reumatologica, Ospedale "Carlo Urbani", Dipartimento Di Scienze Cliniche E Molecolari, Università Politecnica Delle Marche, Via Aldo Moro, 25, 60035, Jesi, Ancona, Italy. dica.marco@yahoo.it.ORCID http://orcid.org/0000-0002-0906-4647
Gabriele PolonaraDipartimento di Scienze Radiologiche, Ospedali Riuniti, Università Politecnica Delle Marche, Ancona, Italia.ORCID http://orcid.org/0000-0002-2866-2749
Giancarlo FacchiniRadiologia Diagnostica ed Interventistica, IRCCS Istituto Ortopedico Rizzoli, Via GC Pupilli 1, 40136, Bologna, Italia.ORCID http://orcid.org/0000-0002-6739-7335
Rita GolfieriUnità di Radiologia, Dipartimento di Medicina Specialistica, Diagnostica E Sperimentale, Ospedale Sant'Orsola, Università Di Bologna, Via Albertoni 15, 40138, Bologna, Italy.ORCID http://orcid.org/0000-0001-8809-9989
Andrea GiovagnoniDipartimento di Scienze Radiologiche, Ospedali Riuniti, Università Politecnica Delle Marche, Ancona, Italia.ORCID http://orcid.org/0000-0002-5264-652X
Marche Polytechnic University · ITIstituto Ortopedico Rizzoli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spondylodiscitis is a complex disease whose diagnosis and management are still challenging. The differentiation between infectious and non-infectious aetiology is mandatory to avoid delays in the treatment of life-threatening infectious conditions. Imaging methods, in particular magnetic resonance imaging (MRI), play a key role in differential diagnosis. MRI provides detailed anatomical information, especially regarding the epidural space and spinal cord, and may allow differential diagnosis by assessing the characteristics of certain infectious and inflammatory/degenerative lesions. In this article, we provide an overview of the radiological characteristics and differentiating features of non-infectious inflammatory spinal disorders and infectious spondylodiscitis, focussing on MRI results and presenting relevant clinical and pathological features that help early diagnosis.

Indexed as

Early DiagnosisDiagnosis, DifferentialDiscitisHumansIntervertebral Disc DegenerationMagnetic Resonance ImagingMagnetic resonance imagingSpondyloarthritidesSpondylodiscitisVertebral infection

Identifiers

PMID33797727
PMCPMC8154816
OpenAlexW3142111619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.