Evidence map›Paper›PMID 33797218›Full record

ArticleACS infectious diseases2021

Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites:

Frederick A Partridge, Carole J R Bataille, Ruth Forman, Amy E Marriott, Josephine Forde-Thomas, Cécile Häberli, Ria L Dinsdale, James D B O'Sullivan, Nicky J Willis, Graham M Wynne and 10 more

Open access · hybridAbstract read
In one paragraph

Article in ACS infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Small Molecule Ligands of the BET-like Bromodomain,Journal of medicinal chemistry · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 2 countries.

Frederick A PartridgeCentre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, London WC1E 6JF, United Kingdom.ORCID 0000-0001-6236-4297
Carole J R BatailleDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, United Kingdom.
Ruth FormanLydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, United Kingdom.
Amy E MarriottCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
Josephine Forde-ThomasInstitute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, Wales SY23 3DA, United Kingdom.
Cécile HäberliDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Socinstrasse 57, Basel CH-4002, Switzerland.
Ria L DinsdaleDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, United Kingdom.
James D B O'SullivanLydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, United Kingdom.
Nicky J WillisDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, United Kingdom.
Graham M WynneDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, United Kingdom.
Helen WhitelandInstitute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, Wales SY23 3DA, United Kingdom.
John ArcherCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
Andrew StevenCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
Jennifer KeiserDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Socinstrasse 57, Basel CH-4002, Switzerland.
Joseph D TurnerCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
Karl F HoffmannInstitute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, Wales SY23 3DA, United Kingdom.ORCID 0000-0002-3932-5502
Mark J TaylorCentre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
Kathryn J ElseLydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, United Kingdom.
Angela J RussellDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, United Kingdom.ORCID 0000-0003-3610-9369
David B SattelleCentre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, London WC1E 6JF, United Kingdom.
Liverpool School of Tropical Medicine · GBUniversity of Oxford · GBAberystwyth University · GBUniversity of Manchester · GBSwiss Tropical and Public Health Institute · CHUniversity College London · GB

Funding

Medical Research Council MR/N022661/1Medical Research Council MR/N024842/1Medical Research Council MR/V034243/1National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/S001131/1Wellcome TrustWellcome Trust 201008/Z/16/Z
6 · The paper itself

Abstract

Nine hundred million people are infected with the soil-transmitted helminths

Indexed as

AnthelminticsBrugia malayiNematospiroides dubiusParasitesAnimalsHumansSchistosoma mansoniTrichurisAnthelminticsanthelminticdrug discoverynematodetrematodeTrichuriswhipworm

Identifiers

PMID33797218
PMCPMC8154432
OpenAlexW3148835767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.