Evidence map›Paper›PMID 33797052›Full record

ReviewReproductive sciences (Thousand Oaks, Calif.)2021

Recent Advancements in Engineered Biomaterials for the Regeneration of Female Reproductive Organs.

Sung Woo Kim, Yoon Young Kim, Hoon Kim, Seung-Yup Ku

Abstract readReview
PubMed Publisher
In one paragraph

Review in Reproductive sciences (Thousand Oaks, Calif.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sung Woo KimDepartment of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, 03080, South Korea.
Yoon Young Kim *Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, 03080, South Korea. yoonykim96@gmail.com.
Hoon Kim *Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, 03080, South Korea. obgyhoon@gmail.com.ORCID 0000-0002-5623-6368
Seung-Yup KuDepartment of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, 03080, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various gynecologic diseases and chemoradiation or surgery for the management of gynecologic malignancies may damage the uterus and ovaries, leading to clinical problems such as infertility or early menopause. Embryo or oocyte cryopreservation-the standard method for fertility preservation-is not a feasible option for patients who require urgent treatment because the procedure requires ovarian stimulation for at least several days. Hormone replacement therapy (HRT) for patients diagnosed with premature menopause is contraindicated for patients with estrogen-dependent tumors or a history of thrombosis. Furthermore, these methods cannot restore the function of the uterus and ovaries. Although autologous transplantation of cryopreserved ovarian tissue is being attempted, it may re-introduce malignant cells after cancer treatment. With the recent development in regenerative medicine, research on engineered biomaterials for the restoration of female reproductive organs is being actively conducted. The use of engineered biomaterials is a promising option in the field of reproductive medicine because it can overcome the limitations of current therapies. Here, we review the ideal properties of biomaterials for reproductive tissue engineering and the recent advancements in engineered biomaterials for the regeneration of female reproductive organs.

Indexed as

Biocompatible MaterialsRegenerationTissue EngineeringAnimalsDecellularized Extracellular MatrixFemaleGenitalia, FemaleGynatresiaHumansInfertility, FemaleStem CellsTissue ScaffoldsUterusBiocompatible MaterialsDecellularized Extracellular MatrixEngineered biomaterialsFemale reproductive organsRegeneration

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.