Trial reportCanadian journal of anaesthesia = Journal canadien d'anesthesie2021
Non-ventilated lung deflation during one-lung ventilation with a double-lumen endotracheal tube: a randomized-controlled trial of occluding the non-ventilated endobronchial lumen before pleural opening.
Trial report in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clamping the Double Lumen Tube : A Novel Technique to Optimize One-Lung Ventilation
Effect of Brief Bronchial Suction on the Quality of Non-Ventilated Lung Collapse and Time to Adequate Surgical Exposure During Uniportal Video-Assisted Thoracoscopic Surgery: a Randomized Patient- and Surgeon-Blinded Trial
Who cites it
18 citing papers in PubMed, 22 citations in OpenAlex.
- The efficacy and safety of extraluminal bronchial blockers in pediatric patients during one-lung ventilation for thoracoscopic surgery.Pediatric surgery international · 2026Trial
- Preconditioning lung collapse: effects of early recruitment maneuvers on lung deflation dynamics during one-lung ventilation.Frontiers in medicine · 2026Trial
- Effects of the disconnection technique and preemptive one-lung ventilation on lung collapse during one-lung ventilation in thoracoscopic surgery.BMC anesthesiology · 2025Trial
- Non-ventilated lung deflation during one-lung ventilation with a double-lumen endotracheal tube: a randomized-controlled trial of occluding the non-ventilated endobronchial lumen before pleural opening.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021Trial
- Optimizing Lung Collapse During One-Lung Ventilation: Physiological Mechanisms and Clinical Strategies: A Narrative Review.Journal of clinical medicine · 2026Review
- Factors associated with selective fiberoptic bronchoscopy use after left double-lumen tube placement.BMC anesthesiology · 2026Observational
- Anesthetic management of a patient with acquired bronchobiliary fistula: a case report.BMC anesthesiology · 2026Article
- One-lung ventilation with intentional closure of the nonventilated lumen in a patient with giant pulmonary bullae undergoing laparoscopic anterior resection: a case report.AME case reports · 2026Article
- Emergency thoracoscopic exploration under nonintubated general anesthesia preserved spontaneous ventilation after bilateral lung transplantation: a rare case report.BMC anesthesiology · 2025Article
- Clinical practice of one-lung ventilation in mainland China: a nationwide questionnaire survey.BMC anesthesiology · 2025Article
- Impact of cardiac factors on central airway anatomical parameters in patients undergoing lung mass surgery.Journal of cardiothoracic surgery · 2025Article
- The impact of suction duration on lung collapse during one-lung ventilation.Frontiers in surgery · 2025Article
- Systematic Review and Meta-Analysis of Efficiency and Safety of Double-Lumen Tube and Bronchial Blocker for One-Lung Ventilation.Journal of clinical medicine · 2023Review
- Article
- [Application and Research Progress of Video Double-lumen Tube in Thoracic Surgery].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2022Review
- Non-ventilated lung airway occlusion during one-lung ventilation: a need for further research?Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021Article
- The need to better understand the physiology of lung collapse during one-lung ventilation.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021Article
- In reply: The need to better understand the physiology of lung collapse during one-lung ventilation.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLung deflation during one-lung ventilation (OLV) is thought to be faster using a double-lumen endotracheal tube (DL-ETT) than with a bronchial blocker, especially when the non-ventilated lumen is opened to allow egress of air from the operative lung. Nevertheless, ambient air can also be entrained into the non-ventilated lumen before pleural opening and subsequently delay deflation. We therefore hypothesized that occluding the non-ventilated DL-ETT lumen during OLV before pleural opening would prevent air entrainment and consequently enhance operative lung deflation during video-assisted thoracoscopic surgery (VATS).
methodsThirty patients undergoing VATS using DL-ETT to allow OLV were randomized to having the lumen of the operative lung either open (control group) or occluded (intervention group) to ambient air. The primary outcome was the time to lung collapse evaluated intraoperatively by the surgeons. The T
resultsThe median [interquartile range] time to lung deflation occurred faster in the intervention group than in the control group (24 [20-37] min vs 54 [48-68] min, respectively; median difference, 30 min; 95% confidence interval [CI], 14 to 46; P < 0.001). The estimated T
conclusionOperative lung deflation during OLV with a DL-ETT is faster when the operative lumen remains closed before pleural opening thus preventing it from entraining ambient air during the closed chest phase of OLV.
trial registrationwww.clinicaltrials.gov (NCT03508050); registered 27 September 2017.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.