Evidence map›Paper›PMID 33796964›Full record

ArticleLasers in medical science2021

Could the photobiomodulation therapy induce angiogenic growth factors expression from dental pulp cells?

Mariel Tavares Bergamo, Luciana Lourenço Ribeiro Vitor, Thiago José Dionísio, Nádia Carolina Teixeira Marques, Rodrigo Cardoso Oliveira, Eloá Cristina Passucci Ambrosio, Vivien Thiemy Sakai, Carlos Ferreira Santos, Natalino Lourenço Neto, Maria Aparecida Andrade Moreira Machado and 1 more

Abstract read
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In one paragraph

Article in Lasers in medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Influence of photobiomodulation therapy on regenerative potential of non-vital mature permanent teeth in healthy canine dogs.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Mariel Tavares BergamoDepartment of Pediatric Dentistry, Orthodontics and Collective Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, São Paulo, 17012-901, Brazil.
Luciana Lourenço Ribeiro VitorSacred Heart University, Bauru, São Paulo, Brazil.
Thiago José DionísioDepartment of Biology Science, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, 17012-901, Brazil.
Nádia Carolina Teixeira MarquesDepartment of Pediatric Dentistry, School of Dentistry, José do Rosário Vellano University, Alfenas, Minas Gerais, Brazil.
Rodrigo Cardoso OliveiraDepartment of Biology Science, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, 17012-901, Brazil.
Eloá Cristina Passucci AmbrosioDepartment of Pediatric Dentistry, Orthodontics and Collective Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, São Paulo, 17012-901, Brazil.
Vivien Thiemy SakaiDepartment of Clinics and Surgery, School of Dentistry, Federal University of Alfenas, Alfenas, Minas Gerais, 37130 000, Brazil.
Carlos Ferreira SantosDepartment of Biology Science, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, 17012-901, Brazil.
Natalino Lourenço NetoDepartment of Pediatric Dentistry, Orthodontics and Collective Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, São Paulo, 17012-901, Brazil.
Maria Aparecida Andrade Moreira MachadoDepartment of Pediatric Dentistry, Orthodontics and Collective Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, São Paulo, 17012-901, Brazil.
Thais Marchini OliveiraDepartment of Pediatric Dentistry, Orthodontics and Collective Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, São Paulo, 17012-901, Brazil. marchini@usp.br.ORCID http://orcid.org/0000-0003-3460-3144
Universidade de São Paulo · BRUniversidade Federal de Alfenas · BRUniversidade José do Rosário Vellano · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/19696-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/11396-3Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/20316-6
6 · The paper itself

Abstract

This study aimed to evaluate the effect of different photobiomodulation (PBM) radiant exposures on the viability, proliferation, and gene expression of pulp fibroblasts from human primary teeth (HPF) involved in the pulp tissue repair. HPF were irradiated with Laser InGaAlP (Twin Flex Evolution, MMOptics®) at 660-nm wavelength (red); single time, continuous mode, 0.04-cm

Indexed as

Low-Level Light TherapyCell ProliferationCell SurvivalDental PulpHumansTooth, DeciduousDental pulpFibroblastFibroblast growth factor-2Low-level light therapyVascular endothelial growth factor A

Identifiers

PMID33796964
OpenAlexW3140651812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.