ArticleNature aging2021
Olfactory perception of food abundance regulates dietary restriction-mediated longevity via a brain-to-gut signal.
Article in Nature aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 52 citations in OpenAlex.
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- Intestinal pathogens override hunger-driven decision-making via immune regulation of central serotonin signaling in C. elegans.Nature communications · 2026Article
- Deciphering the regulatory mechanism of neural behavioral decisions through biogenic amine-mediated modulation of neural circuits inFrontiers in systems neuroscience · 2026Review
- Context-dependent serotonin signaling links dietary quality to foraging decisions.Nature communications · 2025Article
- Impact of bacterial inactivation methods on Caenorhabditis elegans feeding and healthspan.Scientific reports · 2025Article
- Article
- Methionine cycle in C. elegans serotonergic neurons regulates diet-dependent behaviour and longevity through neuron-gut signaling.Nature communications · 2025Article
- TMBIM-2 orchestrates systemic mitochondrial stress response via facilitating Ca2+ oscillations.The Journal of cell biology · 2025Article
- Modulation of C. elegans behavior, fitness, and lifespan by AWB/ASH-dependent death perception.Current biology : CB · 2025Article
- Dietary cinnamon promotes longevity and extends healthspan via mTORC1 and autophagy signaling.Aging cell · 2025Article
- Perception and Longevity Control in Invertebrate Model Organisms-A Mini-Review of Recent Advances.Biomolecules · 2025Review
- A mitochondrial unfolded protein response-independent role of DVE-1 in longevity regulation.Cell reports · 2024Article
- UPReLife · 2024Article
- Exposure to an aversive odor altersmicroPublication biology · 2024Article
- Neural mechanisms of dopamine function in learning and memory inNeuronal signaling · 2024Review
- Article
- BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice.Cell death & disease · 2023Article
- Olfactory chemosensation extends lifespan through TGF-β signaling and UPR activation.Nature aging · 2023Article
- Effects of hunger on neuronal histone modifications slow aging inScience (New York, N.Y.) · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
The role of food nutrients in mediating the positive effect of dietary restriction (DR) on longevity has been extensively characterized, but how non-nutrient food components regulate lifespan is not well understood. Here, we show that food-associated odors shorten the lifespan of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.