Evidence map›Paper›PMID 33796801›Full record

ArticleJournal of the Endocrine Society2021

IGSF1 Does Not Regulate Spermatogenesis or Modify FSH Synthesis in Response to Inhibins or Activins.

Emilie Brûlé, Charlotte A Heinen, Courtney L Smith, Gauthier Schang, Yining Li, Xiang Zhou, Ying Wang, Sjoerd D Joustra, Jan M Wit, Eric Fliers and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Emilie BrûléDepartment of Anatomy and Cell Biology, McGill University, Montréal, Québec H3A 0C7, Canada.
Charlotte A HeinenEmma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Department of Pediatric Endocrinology, 1105 Amsterdam, the Netherlands.
Courtney L SmithDepartment of Pharmacology and Therapeutics, McGill University, Montréal, Québec H3G 1Y6, Canada.
Gauthier SchangDepartment of Pharmacology and Therapeutics, McGill University, Montréal, Québec H3G 1Y6, Canada.
Yining LiDepartment of Pharmacology and Therapeutics, McGill University, Montréal, Québec H3G 1Y6, Canada.
Xiang ZhouDepartment of Pharmacology and Therapeutics, McGill University, Montréal, Québec H3G 1Y6, Canada.
Ying WangDepartment of Pharmacology and Therapeutics, McGill University, Montréal, Québec H3G 1Y6, Canada.
Sjoerd D JoustraDepartment of Medicine, Division of Endocrinology, Leiden University Medical Center, 2300 Leiden, the Netherlands.ORCID https://orcid.org/0000-0002-4733-9031
Jan M WitDepartment of Pediatrics, Leiden University Medical Center, 2300 Leiden, the Netherlands.ORCID https://orcid.org/0000-0002-1715-5020
Eric FliersAmsterdam University Medical Centers, University of Amsterdam, Department of Endocrinology & Metabolism, Meibergdreef 9, 1105 Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0001-8048-9050
Sjoerd ReppingAmsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 Amsterdam, the Netherlands.
A S Paul van TrotsenburgEmma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Department of Pediatric Endocrinology, 1105 Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-9677-7441
Daniel J BernardDepartment of Anatomy and Cell Biology, McGill University, Montréal, Québec H3A 0C7, Canada.ORCID https://orcid.org/0000-0001-5365-5586
McGill University · CAAmsterdam University Medical Centers · NLEmma Kinderziekenhuis · NLLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loss-of-function mutations in the X-linked immunoglobulin superfamily, member 1 (

Indexed as

FSHIGSF1macroorchidismpituitary

Identifiers

PMID33796801
PMCPMC7986638
OpenAlexW3129218974

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.