Evidence map›Paper›PMID 33796463›Full record

ArticleFrontiers in oncology2021

Cytotoxic Effects of Arsenite in Combination With Gamabufotalin Against Human Glioblastoma Cell Lines.

Bo Yuan, Kang Xu, Ryota Shimada, JingZhe Li, Hideki Hayashi, Mari Okazaki, Norio Takagi

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Bo YuanLaboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Josai University, Sakado, Japan.
Kang XuDepartment of Applied Biochemistry, Tokyo University of Pharmacy & Life Sciences, Hachioji, Japan.
Ryota ShimadaDepartment of Applied Biochemistry, Tokyo University of Pharmacy & Life Sciences, Hachioji, Japan.
JingZhe LiBeijing Key Laboratory of Research of Chinese Medicine on Prevention and Treatment for Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing, China.
Hideki HayashiDepartment of Applied Biochemistry, Tokyo University of Pharmacy & Life Sciences, Hachioji, Japan.
Mari OkazakiLaboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Josai University, Sakado, Japan.
Norio TakagiDepartment of Applied Biochemistry, Tokyo University of Pharmacy & Life Sciences, Hachioji, Japan.
Tokyo University of Pharmacy and Life Sciences · JPChinese Academy of Medical Sciences & Peking Union Medical College · CNJosai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma is a fatal primary malignant brain tumor, and the 5-year survival rate of treated glioblastoma patients still remains <5%. Considering the sustained development of metastasis, tumor recurrence, and drug resistance, there is an urgent need for the novel therapeutic approaches to combat glioblastoma. Trivalent arsenic derivative (arsenite, As

Indexed as

arseniteautophagycell cycle arrestcombination therapygamabufotalinglioblastomalactate dehydrogenasep38 MAPK

Identifiers

PMID33796463
PMCPMC8009626
OpenAlexW3138095361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.