Evidence map›Paper›PMID 33796371›Full record

ArticleBiomedical optics express2021

Motion-compensated noninvasive periodontal health monitoring using handheld and motor-based photoacoustic-ultrasound imaging systems.

Moein Mozaffarzadeh, Colman Moore, Erfan Barzegar Golmoghani, Yash Mantri, Ali Hariri, Alec Jorns, Lei Fu, Martin D Verweij, Mahdi Orooji, Nico de Jong and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

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  15. Photoacoustic monitoring of angiogenesis predicts response to therapy in healing wounds.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2022
    Article
  16. Article
  17. Review
  18. Photoacoustic Imaging for Periodontal Disease Examination.Journal of lasers in medical sciences · 2022
    Article
  19. Article
  20. Regional motion correction forBiomedical optics express · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Moein MozaffarzadehLaboratory of Medical Imaging, Department of Imaging Physics, Delft University of Technology, 2628 CJ Delft, The Netherlands.ORCID https://orcid.org/0000-0003-0374-9351
Colman MooreDepartment of NanoEngineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.ORCID https://orcid.org/0000-0002-1809-5955
Erfan Barzegar GolmoghaniDepartment of Electrical and Computer Engineering, Tarbiat Modares University, Tehran, Iran.
Yash MantriDepartment of Bioengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Ali HaririDepartment of NanoEngineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Alec JornsDepartment of NanoEngineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Lei FuDepartment of NanoEngineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Martin D VerweijLaboratory of Medical Imaging, Department of Imaging Physics, Delft University of Technology, 2628 CJ Delft, The Netherlands.
Mahdi OroojiDepartment of Electrical and Computer Engineering, Tarbiat Modares University, Tehran, Iran.
Nico de JongLaboratory of Medical Imaging, Department of Imaging Physics, Delft University of Technology, 2628 CJ Delft, The Netherlands.
Jesse V JokerstDepartment of NanoEngineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
University of California System · USErasmus University Rotterdam · NLTarbiat Modares University · IRDelft University of Technology · NL

Funding

Training in Multi-Scale Analysis of Biological Structure and FunctionT32EB009380 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrew D. McCulloch, Padmini Rangamani · 2009 to 2026
$4.8M
Therapeutic Drug Monitoring with a Wearable Ultrasound-based SensorDP2HL137187 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2016 to 2019
$2.7M
Modeling and analysis of the mechanochemical processes that govern clathrin-mediated endocytosisR01GM132106 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RANGAMANI, PADMINI · 2020 to 2024
$1.5M
Vevo LAZR Photoacoustic Imaging SystemS10OD021821 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HALL, DAVID J · 2016 to 2016
$594k
Non-Invasive Detection and Staging of Decubitus and Diabetic UlcersR21AG065776 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2020 to 2021
$575k
A Miniaturized Tool for Ultrasound Quantification of Periodontal DiseaseR21DE029025 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2019 to 2020
$409k
Molecular Imaging of Gingipain Activity in Advanced PeriodontitisR21DE029917 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2020 to 2021
$406k
NHLBI NIH HHS DP2 HL137187NIA NIH HHS R21 AG065776NIBIB NIH HHS T32 EB009380NIDCR NIH HHS R21 DE029025NIDCR NIH HHS R21 DE029917NIGMS NIH HHS R01 GM132106NIH HHS S10 OD021821
6 · The paper itself

Abstract

Simultaneous visualization of the teeth and periodontium is of significant clinical interest for image-based monitoring of periodontal health. We recently reported the application of a dual-modality photoacoustic-ultrasound (PA-US) imaging system for resolving periodontal anatomy and periodontal pocket depths in humans. This work utilized a linear array transducer attached to a stepper motor to generate 3D images via maximum intensity projection. This prior work also used a medical head immobilizer to reduce artifacts during volume rendering caused by motion from the subject (e.g., breathing, minor head movements). However, this solution does not completely eliminate motion artifacts while also complicating the imaging procedure and causing patient discomfort. To address this issue, we report the implementation of an image registration technique to correctly align B-mode PA-US images and generate artifact-free 2D cross-sections. Application of the deshaking technique to PA phantoms revealed 80% similarity to the ground truth when shaking was intentionally applied during stepper motor scans. Images from handheld sweeps could also be deshaken using an LED PA-US scanner. In

Identifiers

PMID33796371
PMCPMC7984772
OpenAlexW3128426251

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.