ReviewTherapeutic advances in chronic disease2021
The neurological symptoms of COVID-19: a systematic overview of systematic reviews, comparison with other neurological conditions and implications for healthcare services.
Review in Therapeutic advances in chronic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- What are the long-term holistic health consequences of COVID-19 among survivors? An umbrella systematic review.Journal of medical virology · 2022Pooled it
- A mixed-methods analysis of the implementation of a new community long-COVID service during the 2020 pandemic: Learning from practice.PloS one · 2026Article
- SARS-CoV-2 variants mediated tissue-specific metabolic reprogramming determines the disease pathophysiology in a hamster model.Brain, behavior, and immunity · 2025Article
- Treatment refractory acute necrotizing myelitis after COVID-19 vaccine injection: a case report.Annals of medicine and surgery (2012) · 2024Article
- Immune-Mediated Necrotizing Myopathy With Concurrent Statin Use After Routine COVID-19 Inoculation: A Case Report.Cureus · 2023Article
- Neurological Manifestations of Non-Severe COVID-19-A Multidirectional Approach.Brain sciences · 2023Article
- COVID-19, Mental Health, and Chronic Illnesses: A Syndemic Perspective.International journal of environmental research and public health · 2023Review
- Long COVID as a functional somatic symptom disorder caused by abnormally precise prior expectations during Bayesian perceptual processing: A new hypothesis and implications for pandemic response.SAGE open medicine · 2023Review
- Ultrasonography Assessment Based on Muscle Thickness and Echo Intensity in Post-Polio Patients.Diagnostics (Basel, Switzerland) · 2022Article
- Review
- Neuropsychologic Profiles and Cerebral Glucose Metabolism in Neurocognitive Long COVID Syndrome.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Article
- Post-COVID-19 Condition: Where Are We Now?Life (Basel, Switzerland) · 2022Review
- COVID-19 atypical Parsonage-Turner syndrome: a case report.BMC neurology · 2022Article
- Guillain-Barre syndrome (GBS) associated with COVID-19 infection that resolved without treatment in a child.BMJ case reports · 2022Article
- Perspective: Drawing on Findings From Critical Illness to Explain Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.Frontiers in medicine · 2022Article
- Post-COVID symptoms of potential peripheral nervous and muscular origin.Neurology perspectives · 2021Review
- Outpatient Management of COVID-19 Disease: A Holistic Patient-Centered Proposal Based on the Greek Experience.Journal of personalized medicine · 2021Review
- Substance use, mental disorders and COVID-19: a volatile mix.Current opinion in psychiatry · 2021Review
- Hypothesis: Mechanisms That Prevent Recovery in Prolonged ICU Patients Also Underlie Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).Frontiers in medicine · 2021Article
- Exploring the Neuropsychiatric Sequalae of Perceived COVID-19 Exposure in College Students: A Pilot Digital Phenotyping Study.Frontiers in psychiatry · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsIn response to the rapid spread of COVID-19, this paper provides health professionals with better accessibility to available evidence, summarising findings from a systematic overview of systematic reviews of the neurological symptoms seen in patients with COVID-19. Implications of so-called 'Long Covid' on neurological services and primary care and similarities with other neurological disorders are discussed.
methodsFirstly, a systematic overview of current reviews of neurological symptoms of COVID-19 was conducted. Secondly, the implications of these findings are discussed in relation to the potential effect on neurological services and the similarities in the experience of patients with COVID-19 and those with other neurological disorders. A total of 45 systematic reviews were identified within seven databases, published between 11 April 2020 and 15 October 2020, following a search in June 2020, updated on 20 October 2020.
resultsThe results indicated that COVID-19 exhibits two types of neurological symptoms; life-threatening symptoms such as Guillain-Barre Syndrome (GBS) and encephalitis, and less devastating symptoms such as fatigue and myalgia. Many of these so-called lesser symptoms appear to be emerging as longer-term for some sufferers and have been recently labelled Long Covid. When compared, these less devastating symptoms are very similar to other neurological conditions such as chronic fatigue syndrome (CFS) and functional neurological disorder (FND).
conclusionImplications for neurological healthcare services in the United Kingdom (UK) may include longer waiting times and a need for more resources (including more qualified health professionals). There is also a possible change-effect on health professionals' perceptions of other neurological conditions such as CFS and FND. Future research is recommended to explore changes in health professionals' perceptions of neurological symptoms because of COVID-19.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.