ReviewWorld journal of gastrointestinal surgery2021
Paraesophageal hernia and iron deficiency anemia: Mechanisms, diagnostics and therapy.
Review in World journal of gastrointestinal surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Cameron Lesions: Endoscopic Characteristics, Clinical Profile, and Therapeutic Implications-A Retrospective Study of 43 Patients.Diagnostics (Basel, Switzerland) · 2026Article
- Surgical repair of paraesophageal hernia resolves unexplained iron deficiency anemia in the vast majority of patients: a propensity-matched multicenter study.Surgical endoscopy · 2026Article
- The "ABCD" framework for assessment: a task-oriented approach to reconcile multimodal diagnostic discordance.Frontiers in medicine · 2026Review
- Iron Deficiency Anemia in Pediatric Gastroesophageal Reflux Disease.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is ample clinical evidence suggesting that the presence of large axial or paraesophageal hernias may lead to iron deficiency anemia. So-called Cameron lesions, as well as other small mucosa erosions, in the sliding area of these diaphragmatic hernias lead to invisible chronic blood loss and consequently to iron depletion. While the spectrum of symptoms in these patients is large, anemia is often not the only indication and typically not the primary indication for surgical correction of diaphragmatic hernias. Drug treatment with proton pump inhibitors and iron substitution can alleviate anemia, but this is not always successful. To exclude other possible bleeding sources in the gastrointestinal tract, a comprehensive diagnostic program is necessary and reviewed in this manuscript. Additionally, we discuss controversies in the surgical management of paraesophageal hernias.
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Registered trials
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