Evidence map›Paper›PMID 33796207›Full record

ArticleECS transactions2020

Insights on the Lower Critical Solution Temperature Behavior of pNIPAM in an Applied Electric Field.

Joelle M J LaFreniere, Emma J Roberge, Tianyu Ren, W Rudolph Seitz, Eva Rose M Balog, Jeffrey M Halpern

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ECS transactions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joelle M J LaFreniereDepartment of Mechanical Engineering, University of New Hampshire, Durham, NH, 03824, USA.
Emma J RobergeDepartment of Chemical Engineering, University of New Hampshire, Durham, NH, 03824, USA.
Tianyu RenDepartment of Chemistry, University of New Hampshire, Durham, NH, 03824, USA.
W Rudolph SeitzDepartment of Chemistry, University of New Hampshire, Durham, NH, 03824, USA.
Eva Rose M BalogDepartment of Chemistry and Physics, University of New England, Biddeford, ME, 04005, USA.
Jeffrey M HalpernDepartment of Chemical Engineering, University of New Hampshire, Durham, NH, 03824, USA.

Funding

TLR-TRIF mediated induction of GLI3 modulates innate inflammatory responsesP20GM113131 · NIGMS · UNIVERSITY OF NEW HAMPSHIRE · PI DON Michael WOJCHOWSKI · 2017 to 2026
$22.8M
NIGMS NIH HHS P20 GM113131
6 · The paper itself

Abstract

Poly(N-isopropylacrylamide), or pNIPAM, is a free-radical polymer that is commonly studied for uses in surface coatings, tissue engineering, energy storage, biosensing, and more, due to its temperature responsiveness. pNIPAM is known to solubilize at temperatures below its lower critical solution temperature (LCST) and agglomerate above its LCST. This behavior has been shown to be reproducible and reversible. We confirmed this reversibility and the value of the LCST by performing dynamic light scattering (DLS) with a temperature sweep (increase and decrease). However, performing the same experiment under an applied voltage from copper electrodes, we observed a decrease in the LCST of pNIPAM and irreversible aggregation. Here we present preliminary data comparing the LCST behavior of pNIPAM in the presence of applied voltage using copper, aluminum, and carbon electrodes. We present data in support of the hypothesis that a phenomenon is occurring specifically with the use of copper electrodes that is altering pNIPAM LCST behavior.

Identifiers

PMID33796207
PMCPMC8011545

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.